Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome

被引：144

作者：

Cui, W

Fan, Y

Wu, W

Zhang, F

Wang, JY

Ni, AP

机构：

[1] Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Clin Lab, Beijing 100730, Peoples R China

[2] Chinese Acad Med Sci, Beijing 100037, Peoples R China

来源：

CLINICAL INFECTIOUS DISEASES | 2003年 / 37卷 / 06期

关键词：

D O I：

10.1086/378587

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In a cohort of 38 patients with severe acute respiratory syndrome (SARS), we observed leukopenia in 47% of patients, lymphopenia in 84%, and T lymphopenia in 95%. CD4(+) T lymphocyte levels were reduced in 100% of patients, CD8(+) T lymphocyte levels were reduced in 87%, B lymphocyte levels were reduced in 76%, and natural killer cell levels were reduced in 55%. Our data suggested that these patients' immune systems were impaired during the course of SARS. The absolute counts of lymphocyte subsets demonstrated a clinical significance for patients with SARS.

引用

页码：857 / 859

页数：3

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