Restoring Fertility with Human Induced Pluripotent Stem Cells: Are We There Yet?

被引:13
作者
Gell, Joanna J. [1 ,2 ,5 ]
Clark, Amander T. [3 ,4 ,5 ]
机构
[1] Div Hematol Oncol, Dept Pediat, Los Angeles, CA USA
[2] David Geffen Sch Med, Los Angeles, CA USA
[3] Univ Calif Los Angeles, Dept Mol Cell & Dev Biol, Los Angeles, CA 90095 USA
[4] Univ Calif Los Angeles, Mol Biol Inst, Los Angeles, CA 90095 USA
[5] Univ Calif Los Angeles, Eli & Edythe Broad Ctr Regenerat Med & Stem Cell, Los Angeles, CA 90095 USA
关键词
D O I
10.1016/j.stem.2018.11.003
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Overcoming infertility with assisted reproduction requires high-quality eggs and sperm. For those young women who no longer make functional eggs, the hope of conceiving a biological child just got one step closer with a recent publication in Science from Yamashiro et al. (2018).
引用
收藏
页码:777 / 779
页数:3
相关论文
共 9 条
[1]   New insights into the generation and role of de novo mutations in health and disease [J].
Acuna-Hidalgo, Rocio ;
Veltman, Joris A. ;
Hoischen, Alexander .
GENOME BIOLOGY, 2016, 17
[2]  
[Anonymous], 2017, 2015 ASS REPR TECHN
[3]   Germline competency of human embryonic stem cells depends on eomesodermin [J].
Chen, Di ;
Liu, Wanlu ;
Lukianchikov, Anastasia ;
Hancock, Grace V. ;
Zimmerman, Jill ;
Lowe, Matthew G. ;
Kim, Rachel ;
Galic, Zoran ;
Irie, Naoko ;
Surani, M. Azim ;
Jacobsen, Steven E. ;
Clark, Amander T. .
BIOLOGY OF REPRODUCTION, 2017, 97 (06) :850-861
[4]  
Cyranoski D, 2018, NATURE, DOI [10.1038/d41586-018-06847-7, DOI 10.1038/D41586-018-06847-7]
[5]   SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate [J].
Irie, Naoko ;
Weinberger, Leehee ;
Tang, Walfred W. C. ;
Kobayashi, Toshihiro ;
Viukov, Sergey ;
Manor, Yair S. ;
Dietmann, Sabine ;
Hanna, Jacob H. ;
Surani, M. Azim .
CELL, 2015, 160 (1-2) :253-268
[6]   Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells [J].
Sasaki, Kotaro ;
Yokobayashi, Shihori ;
Nakamura, Tomonori ;
Okamoto, Ikuhiro ;
Yabuta, Yukihiro ;
Kurimoto, Kazuki ;
Ohta, Hiroshi ;
Moritoki, Yoshinobu ;
Iwatani, Chizuru ;
Tsuchiya, Hideaki ;
Nakamura, Shinichiro ;
Sekiguchi, Kiyotoshi ;
Sakuma, Tetsushi ;
Yamamoto, Takashi ;
Mori, Takahide ;
Woltjen, Knut ;
Nakagawa, Masato ;
Yamamoto, Takuya ;
Takahashi, Kazutoshi ;
Yamanaka, Shinya ;
Saitou, Mitinori .
CELL STEM CELL, 2015, 17 (02) :178-194
[7]   International incidence of childhood cancer, 2001-10: a population-based registry study [J].
Steliarova-Foucher, Eva ;
Colombet, Murielle ;
Ries, Lynn A. G. ;
Moreno, Florencia ;
Dolya, Anastasia ;
Bray, Freddie ;
Hesseling, Peter ;
Shin, Hee Young ;
Stiller, Charles A. .
LANCET ONCOLOGY, 2017, 18 (06) :719-731
[8]   Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile [J].
Sugawa, Fumihiro ;
Arauzo-Bravo, Marcos J. ;
Yoon, Juyong ;
Kim, Kee-Pyo ;
Aramaki, Shinya ;
Wu, Guangming ;
Stehling, Martin ;
Psathaki, Olympia E. ;
Huebner, Karin ;
Schoeler, Hans R. .
EMBO JOURNAL, 2015, 34 (08) :1009-1024
[9]   Generation of human oogonia from induced pluripotent stem cells in vitro [J].
Yamashiro, Chika ;
Sasaki, Kotaro ;
Yabuta, Yukihiro ;
Kojima, Yoji ;
Nakamura, Tomonori ;
Okamoto, Ikuhiro ;
Yokobayashi, Shihori ;
Murase, Yusuke ;
Ishikura, Yukiko ;
Shirane, Kenjiro ;
Sasaki, Hiroyuki ;
Yamamoto, Takuya ;
Saitou, Mitinori .
SCIENCE, 2018, 362 (6412) :356-359