Crohn's disease defined in three elderly sisters

被引：1

作者：

Freeman, HJ ^{[1
]}

机构：

[1] Univ British Columbia, Dept Med, Div Gastroenterol, Vancouver, BC, Canada

来源：

CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | 2005年 / 19卷 / 04期

关键词：

Crohn's disease; Crohn's disease in the elderly; familial Crohn's disease; phenotypical expression of Crohn's disease;

D O I：

10.1155/2005/241486

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Three elderly sisters presented with symptomatic Crohn's disease. All had ileocolic involvement, and granulomatous inflammation was documented in endoscopic biopsies or surgically resected intestinal specimens. The present report documents the unusual occurrence of very late phenotypical expression of familial ileocolic Crohn's disease. The observations presented here reflect a possible gene-based predisposition to Crohn's disease or, alternatively, disease clustering related to a commonly shared environmental factor.

引用

页码：251 / 252

页数：2

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