A review of the antimicrobial activity of thermodynamically stable microemulsions

被引:15
作者
Al-Adham, I. S. I. [1 ]
Jaber, N. [2 ]
Al-Remawi, M. [1 ]
Al-Akayleh, F. [1 ]
Al-Kaissi, E. [1 ]
Ali Agha, A. S. A. [1 ]
Fitzsimmons, L. B. [3 ]
Collier, P. J. [1 ,3 ]
机构
[1] Univ Petra, Fac Pharm & Med Sci, Amman, Jordan
[2] Al Zaytoonah Univ Jordan, Fac Pharm, Amman, Jordan
[3] Abertay Univ, Sch Sci & Engn, Dundee, Scotland
关键词
antimicrobial; membrane-active; microemulsion; mode of action; preservative; DRUG-DELIVERY; SURFACTANT NANOEMULSION; ANTIBACTERIAL ACTIVITY; OIL; SYSTEM; OPTIMIZATION; TERMINOLOGY; MECHANISM; EFFICACY; MEDIA;
D O I
10.1111/lam.13570
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Microemulsions are thermodynamically stable, transparent, isotropic mixtures of oil, water and surfactant (and sometimes a co-surfactant), which have shown potential for widespread application in disinfection and self-preservation. This is thought to be due to an innate antimicrobial effect. It is suggested that the antimicrobial nature of microemulsions is the result of a combination of their inherent kinetic energy and their containing surfactants, which are known to aid the disruption of bacterial membranes. This review examines the contemporary evidence in support of this theory.
引用
收藏
页码:537 / 547
页数:11
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