Ischemia-modified albumin as an oxidative stress marker in preeclampsia

被引:45
|
作者
Ustun, Yusuf [1 ]
Engin-Ustun, Yaprak [1 ]
Ozturk, Ozlem [2 ]
Alanbay, Ibrahim [3 ]
Yaman, Halil [2 ]
机构
[1] Inonu Univ, Sch Med, Dept Obstet & Gynecol, Malatya, Turkey
[2] Gulhane Mil Med Acad, Dept Biochem, Ankara, Turkey
[3] Gulhane Mil Med Acad, Dept Obstet & Gynecol, Ankara, Turkey
来源
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2011年 / 24卷 / 03期
关键词
Preeclampsia; ischaemia-modified albumin; ACUTE CORONARY SYNDROME; BIOMARKERS; PREGNANCY; ASSOCIATION; OUTCOMES; LIPIDS;
D O I
10.3109/14767058.2010.497879
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Methods. aEuro integral Serum ischaemia-modified albumin levels were measured in 18 normotensive and 36 preeclamptic pregnant women by enzyme linked immuno-sorbent assay. Patients were subdivided as having either mild (n == 18) or severe preeclampsia (n == 18). Receiver operating characteristic curve was constructed, and sensitivity and specificity were calculated based on the best cut-off. Results. aEuro integral IMA levels were significantly higher in the mild and severe preeclamptic groups than in the control group. IMA with a cut-off point of 0.31 identified women with preeclampsia with sensitivity 80%% and specificity 77.8%%. Conclusion. aEuro integral Our study demonstrates that serum levels of IMA correlate with severity of preeclampsia.
引用
收藏
页码:418 / 421
页数:4
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