Stability study of virus replication model

被引:0
作者
Khan, Q. J. A. [1 ]
Balakrishnan, E. [1 ]
Al Sinani, Nayif Khamis [1 ]
机构
[1] Sultan Qaboos Univ, Coll Sci, Dept Math, Muscat, Oman
来源
JOURNAL OF MATHEMATICS AND COMPUTER SCIENCE-JMCS | 2020年 / 26卷 / 03期
关键词
Stability; bifurcation; virus; time-delay; FOOD-CHAIN MODELS; HIV-INFECTION; HOPF-BIFURCATION; VIRAL DYNAMICS; ANTIRETROVIRAL THERAPY; MATHEMATICAL-MODEL; DELAY; RESPONSES;
D O I
10.22436/jmcs.026.03.01
中图分类号
O1 [数学];
学科分类号
0701 ; 070101 ;
摘要
An HIV infection model with time delay in which uninfected cells become infected cells is analysed. We studied conditions under which steady states will be asymptotically stable. We also examined that for endemically infected equilibrium a critical value of time delay may occur. The steady state will be asymptotically stable when delay is less than a critical value. Else the uninfected cells, infected cells, free virus, and CTLs may undergo cyclic oscillations. We estimate the delay length to maintain stability. Numerical simulations are done to aid mathematical findings.
引用
收藏
页码:196 / 209
页数:14
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