Full-range k-domain linearization in spectral-domain optical coherence tomography

被引:65
作者
Jeon, Mansik [2 ]
Kim, Jeehyun [2 ]
Jung, Unsang [2 ]
Lee, Changho [2 ]
Jung, Woonggyu [1 ]
Boppart, Stephen A. [1 ,3 ]
机构
[1] Univ Illinois, Beckman Inst Adv Sci & Technol, Urbana, IL 61801 USA
[2] Kyungpook Natl Univ, Sch Elect Engn & Comp Sci, Taegu, South Korea
[3] Univ Illinois, Dept Elect & Comp Engn Bioengn & Internal Med, Urbana, IL 61801 USA
基金
美国国家卫生研究院; 新加坡国家研究基金会;
关键词
D O I
10.1364/AO.50.001158
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
A full-bandwidth k-domain linearization method for spectral-domain optical coherence tomography (SD-OCT) is demonstrated. The method uses information of the wavenumber-pixel-position provided by a translating-slit-based wavelength filter. For calibration purposes, the filter is placed either after a broad-band source or at the end of the sample path, and the filtered spectrum with a narrowed line width (similar to 0.5 nm) is incident on a line-scan camera in the detection path. The wavelength-swept spectra are co-registered with the pixel positions according to their central wavelengths, which can be automatically measured with an optical spectrum analyzer. For imaging, the method does not require a filter or a software recalibration algorithm; it simply resamples the OCT signal from the detector array without employing rescaling or interpolation methods. The accuracy of k-linearization is maximized by increasing the k-linearization order, which is known to be a crucial parameter for maintaining a narrow point-spread function ( PSF) width at increasing depths. The broadening effect is studied by changing the k-linearization order by undersampling to search for the optimal value. The system provides more position information, surpassing the optimum without compromising the imaging speed. The proposed full-range k-domain linearization method can be applied to SD-OCT systems to simplify their hardware/software, increase their speed, and improve the axial image resolution. The experimentally measured width of PSF in air has an FWHM of 8 mu m at the edge of the axial measurement range. At an imaging depth of 2.5 mm, the sensitivity of the full-range calibration case drops less than 10 dB compared with the uncompensated case. (C) 2011 Optical Society of America
引用
收藏
页码:1158 / 1163
页数:6
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