Correlation between Serum 25-Hydroxyvitamin D Levels and Quadriceps Muscle Strength in Elderly Cretans

被引:20
作者
Dretakis, O. E. [1 ]
Tsatsanis, C. [1 ]
Fyrgadis, A. [2 ]
Drakopoulos, C. G. [1 ]
Steriopoulos, K. [2 ]
Margioris, A. N. [1 ]
机构
[1] Univ Crete, Dept Clin Chem, Sch Med, GR-71003 Iraklion, Crete, Greece
[2] Univ Hosp Crete, Dept Orthopaed Traumatol, Iraklion, Crete, Greece
关键词
VITAMIN D; ELDERLY PATIENTS; QUADRICEPS MUSCLE STRENGTH; VITAMIN-D DEFICIENCY; SECONDARY HYPERPARATHYROIDISM; PARATHYROID-HORMONE; PHYSICAL-ACTIVITY; HYPOVITAMINOSIS D; HIP-FRACTURES; D-RECEPTOR; BONE LOSS; MYOPATHY; CALCIUM;
D O I
10.1177/147323001003800530
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Vitamin D deficiency is associated with osteomalacic myopathy, and muscle weakness related to vitamin D deficiency has been implicated as a possible risk factor for falls in the elderly. This study investigated the possible correlation between serum 25-hydroxyvitamin D (25[OH]D) concentration and quadriceps muscle strength in ambulatory community dwelling Cretan men (n = 13) and women (n = 35) aged >= 65 years. Quadriceps muscle strength was measured isometrically using Cybex 6000 apparatus. The mean serum 25(OH)D concentration was significantly higher in men than in women (76.00 versus 49.11 nmol/l, respectively). Serum 25(OH)D values were <50 nmol/l in 15% of men and in 60% of women. Serum 25(OH)D concentration correlated positively with quadriceps muscle strength. In conclusion, vitamin D deficiency was common in the study participants despite the high levels of sunlight in Crete. Serum 25(OH)D levels were positively correlated with muscle strength.
引用
收藏
页码:1824 / 1834
页数:11
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