Neonatal Outcomes with the Use of Lamotrigine for Bipolar Disorder in Pregnancy and Breastfeeding: A Case Series and Review of the Literature

被引：0
作者：
Wakil, Laura [1 ]
Epperson, C. Neill [2 ]
Gonzalez, Juan [3 ]
O'Reardon, John P. [1 ]
Kim, Deborah R. [1 ]
机构：
[1] Univ Penn, Dept Psychiat, Philadelphia, PA 19104 USA
[2] Yale Univ, Dept Psychiat, New Haven, CT 06520 USA
[3] Univ Penn, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
来源：
PSYCHOPHARMACOLOGY BULLETIN | 2009年 / 42卷 / 03期
关键词：
lamotrigine; breastfeeding; pregnancy; bipolar disorder; neonatal outcomes; ANTIEPILEPTIC DRUGS; FETAL EXPOSURE; POSTPARTUM; WOMEN; RISK; MALFORMATIONS; MONOTHERAPY; CHILDBIRTH; MANAGEMENT; IMPACT;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The treatment of bipolar disorder in pregnant women and the postpartum period is a complex clinical issue requiring careful consideration of the risks involved in using psychotropic medications versus the benefits of successfully managing this chronic illness. We present three cases of women exposed to lamotrigine during pregnancy and breastfeeding, with follow up of their infants until 15-18 months of development. Psychopharmacology Bulletin. 2009; 423): 91-98.
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收藏
页码：91 / 98
页数：8
相关论文
共 30 条
  • [1] Risk factors associated with childbearing-related episodes in women with bipolar disorder
    Akdeniz, F
    Vahip, S
    Pirildar, S
    Vahip, I
    Doganer, I
    Bulut, I
    [J]. PSYCHOPATHOLOGY, 2003, 36 (05) : 234 - 238
  • [2] Lamotrigine monotherapy in children
    Barron, TF
    Hunt, SL
    Hoban, TF
    Price, ML
    [J]. PEDIATRIC NEUROLOGY, 2000, 23 (02) : 160 - 163
  • [3] Mood stabilizers during breastfeeding: A review
    Chaudron, LH
    Jefferson, JW
    [J]. JOURNAL OF CLINICAL PSYCHIATRY, 2000, 61 (02) : 79 - 90
  • [4] Effect of dose on the frequency of major birth defects following fetal exposure to lamotrigine monotherapy in an international observational study
    Cunnington, Marianne
    Ferber, Sandy
    Quartey, George
    [J]. EPILEPSIA, 2007, 48 (06) : 1207 - 1210
  • [5] Does lamotrigine use in pregnancy increase orofacial cleft risk relative to other malformations?
    Dolk, H.
    Jentink, J.
    Loane, M.
    Morris, J.
    de Jong-van den Berg, L. T. W.
    [J]. NEUROLOGY, 2008, 71 (10) : 714 - 722
  • [6] The impact of reproductive events on the course of bipolar disorder in women
    Freeman, MP
    Smith, KW
    Freeman, SA
    McElroy, SL
    Kmetz, GF
    Wright, R
    Keck, PE
    [J]. JOURNAL OF CLINICAL PSYCHIATRY, 2002, 63 (04) : 284 - 287
  • [7] Gartner LM, 2005, PEDIATRICS, V115, P496, DOI [10.1542/peds.2011-3552, 10.1542/peds.2004-2491]
  • [8] Prophylactic treatment of bipolar disorder in pregnancy and breastfeeding: focus on emerging mood stabilizers
    Gentile, Salvatore
    [J]. BIPOLAR DISORDERS, 2006, 8 (03) : 207 - 220
  • [9] Antiepileptic drug teratogenesis: What are the risks for congenital malformations and adverse cognitive outcomes?
    Harden, Cynthia L.
    [J]. EPILEPSY IN WOMEN: THE SCIENTIFIC BASIS FOR CLINICAL MANAGEMENT, 2008, 83 : 205 - 213
  • [10] Bipolar disorder and childbirth: the importance of recognising risk
    Jones, I
    Craddock, N
    [J]. BRITISH JOURNAL OF PSYCHIATRY, 2005, 186 : 453 - 454
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