rs4147929 variant minor allele increases ABCA7 gene expression and ABCA7 shows increased gene expression in Alzheimer's disease patients compared with controls

被引：12
|
作者：
Liu, Guiyou [1 ,2 ,3 ]
Zhang, Haihua [2 ,3 ]
Liu, Bian [1 ,3 ]
Wang, Tao [4 ,5 ]
Han, Zhifa [6 ,7 ,8 ]
Ji, Xunming [1 ,2 ,3 ,9 ]
机构：
[1] Capital Med Univ, Xuanwu Hosp, Dept Neurol, Room 1037,Guanganmennei St, Beijing 100053, Peoples R China
[2] Capital Med Univ, Beijing Inst Brain Disorders, Beijing 100069, Peoples R China
[3] Capital Med Univ, Xuanwu Hosp, Natl Engn Lab Internet Med Diag & Treatment Techn, Beijing 100053, Peoples R China
[4] Peking Univ, Acad Adv Interdisciplinary Studies, Beijing, Peoples R China
[5] Chinese Inst Brain Res, Beijing, Peoples R China
[6] Tsinghua Univ, Sch Pharmaceut Sci, Sch Med, THU PKU Ctr Life Sci, Beijing, Peoples R China
[7] Chinese Acad Med Sci, Inst Basic Med Sci, State Key Lab Med Mol Biol, Beijing, Peoples R China
[8] Peking Union Med Coll, Dept Pathophysiol, Beijing, Peoples R China
[9] Capital Med Univ, Xuanwu Hosp, Dept Neurosurg, Beijing 100053, Peoples R China
来源：
ACTA NEUROPATHOLOGICA | 2020年 / 139卷 / 05期
基金：
英国惠康基金; 中国国家自然科学基金; 英国医学研究理事会;
关键词：
Alzheimer's disease; ABCA7; Gene expression; rs4147929; variant; eQTLs analysis; METHYLATION; RISK; LOCI;
D O I：
10.1007/s00401-020-02135-9
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：937 / 940
页数：4
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