A new sesquiterpene isolated from Lindera aggregata (Sims) Kosterm.

被引:24
作者
Cheng, Xian-Long [1 ]
Ma, Shuang-Cheng [1 ]
Wei, Feng [1 ]
Wang, Gang-Li [1 ]
Xiao, Xin-Yue [1 ]
Lin, Rui-Chao [1 ]
机构
[1] Natl Inst Control Pharmaceut & Biol Prod, Dept Chinese Mat Med & Nat Prod, Beijing 100050, Peoples R China
关键词
lindera aggregate; Lauraceae; sesquiterpene; neolindenenonelactone;
D O I
10.1248/cpb.55.1390
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new sesquiterpene, neolindenenonelactone (1), was first isolated from the dried roots of Lindera aggregata (SIMS) KOSTERM., along with four known compounds, linderane (2), isolinderalactone (3), linderalactone (4), and 8-hydroxylindestenolide (5). Their chemical structures were elucidated using spectral analysis of fast atom bombardment mass spectroscopy, one-dimensional nuclear magnetic resonance spectroscopy and two-dimensional-nuclear magnetic resonance spectroscopy including H-1-NMR, C-13-NMR, distortionless enhancement by polarization transfer, heteronuclear multiple-bond coherence, and single-crystal X-ray diffraction techniques.
引用
收藏
页码:1390 / 1392
页数:3
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