Convenient Synthesis of New Heterocycles Containing the Quinoxaline Ring System

被引:1
作者
Mohamed, Hanan A. [1 ,2 ]
Alotaibi, Mohammad Hayal [3 ]
Kariuki, Benson M. [4 ]
El-Hiti, Gamal A. [5 ]
机构
[1] Natl Res Ctr, Appl Organ Chem Dept, Giza, Egypt
[2] Shaqra Univ, Coll Sci & Humanities, Dept Chem, Duwadimi, Saudi Arabia
[3] King Abdulaziz City Sci & Technol, Natl Ctr Petrochem Technol, POB 6086, Riyadh 11442, Saudi Arabia
[4] Cardiff Univ, Sch Chem, Main Bldg,Pk Pl, Cardiff CF10 3AT, S Glam, Wales
[5] King Saud Univ, Coll Appl Med Sci, Dept Optometry, POB 10219, Riyadh 11433, Saudi Arabia
关键词
Quinoxaline-2,3-dithiol; X-ray crystal structure; heterocycles; 1,2,3-triazole; 2-oxo-N '-phenylpropanehydrazonoyl chloride; Spectroscopic methods; ONE-POT SYNTHESIS; BIOLOGICAL-ACTIVITY; MILD-STEEL; DERIVATIVES; OXIDATION; CORROSION; CONDENSATION; CYCLIZATION; PORPHYRINS; LITHIATION;
D O I
10.2174/1570178616666190311161505
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The aim of the current article was to describe simple procedures for the synthesis of new heterocycles incorporating the quinoxaline moiety using benzene-1,2-diamine and quinoxaline-2,3-dithiol as precursors. Simple synthetic methods are described for the synthesis of new heterocycles using commercially available chemicals. Also, the new compounds were determined using analytical and spectroscopic methods including single X-ray crystal structures. A series of new heterocycles containing the quinoxaline nucleus have been synthesized in good yields using simple and convenient procedures. A process has been described for the synthesis of new heterocycles containing the quinoxaline moiety that might be difficult to synthesize by other routes.
引用
收藏
页码:121 / 126
页数:6
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