One-pot, four-component reaction of aryl aldehydes, aryl ketones, phosphorus trichloride, and acetonitrile catalyzed by acetyl chloride:: Synthesis of β-acetamido ketones

被引：9

作者：

Anary-Abbasinejad, Mohammad ^{[1
]}

Saidipoor, Azimeh ^{[1
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Yazd Branch, POB 89195 155, Yazd, Iran

来源：

SYNTHETIC COMMUNICATIONS | 2008年 / 38卷 / 03期

关键词：

beta-acetamido ketones; Dakin - West reaction; phosphorus trichloride; silicaphosphine; silphos;

D O I：

10.1080/00397910701767064

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The one-pot, four-component reaction of aryl aldehydes, aryl ketones, phosphorus trichloride, and acetonitrile, catalyzed by acetyl chloride, affords beta-acetamido ketones in good to excellent yields. Silicaphosphine (silphos), [P(Cl)(3-n)(SiO2)(n)], can also be used effectively as a solid-supported reagent instead of phosphorus trichloride.

引用

页码：354 / 360

页数：7

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