Malaria Elimination 3 Operational strategies to achieve and maintain malaria elimination

被引:285
作者
Moonen, Bruno [1 ,2 ]
Cohen, Justin M. [3 ]
Snow, Robert W. [4 ,5 ]
Slutsker, Laurence [6 ]
Drakeley, Chris [7 ]
Smith, David L. [8 ,9 ]
Abeyasinghe, Rabindra R. [10 ]
Henry Rodriguez, Mario [11 ]
Maharaj, Rajendra [12 ]
Tanner, Marcel [13 ,14 ]
Targett, Geoffrey [7 ]
机构
[1] Clinton Hlth Access Initiat, Nairobi, Kenya
[2] Univ Calif San Francisco, Global Hlth Grp, San Francisco, CA 94143 USA
[3] Clinton Hlth Access Initiat, Boston, MA USA
[4] Kenya Govt Med Res Ctr, Ctr Geog Med, Malaria Publ Hlth & Epidemiol Grp, Nairobi, Kenya
[5] Univ Oxford, Nuffield Dept Clin Med, Ctr Trop Med, Oxford, England
[6] Ctr Dis Control & Prevent, Atlanta, GA USA
[7] London Sch Hyg & Trop Med, Fac Infect & Trop Dis, London WC1, England
[8] Univ Florida, Dept Biol, Gainesville, FL USA
[9] Univ Florida, Emerging Pathogens Inst, Gainesville, FL USA
[10] Minist Hlth, Colombo, Sri Lanka
[11] Natl Inst Publ Hlth, Cuernavaca, Morelos, Mexico
[12] MRC, Durban, Kwazulu Natal, South Africa
[13] Swiss Trop & Publ Hlth Inst, Basel, Switzerland
[14] Univ Basel, Basel, Switzerland
基金
美国国家卫生研究院; 比尔及梅琳达.盖茨基金会; 英国惠康基金;
关键词
PLASMODIUM-VIVAX-MALARIA; FALCIPARUM-MALARIA; PRIMAQUINE THERAPY; TREATMENT-SEEKING; GAMETOCYTE CARRIAGE; ANTIMALARIAL-DRUGS; RISK-FACTORS; TRANSMISSION; SURVEILLANCE; INFECTION;
D O I
10.1016/S0140-6736(10)61269-X
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Present elimination strategies are based on recommendations derived during the Global Malaria Eradication Program of the 1960s. However, many countries considering elimination nowadays have high intrinsic transmission potential and, without the support of a regional campaign, have to deal with the constant threat of imported cases of the disease, emphasising the need to revisit the strategies on which contemporary elimination programmes are based. To eliminate malaria, programmes need to concentrate on identification and elimination of foci of infections through both passive and active methods of case detection. This approach needs appropriate treatment of both clinical cases and asymptomatic infections, combined with targeted vector control. Draining of infectious pools entirely will not be sufficient since they could be replenished by imported malaria. Elimination will thus additionally need identification and treatment of incoming infections before they lead to transmission, or, more realistically, embarking on regional initiatives to dry up importation at its source.
引用
收藏
页码:1592 / 1603
页数:12
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