Linear chaining of etienic acid derivatives with the amide bond.: Synthesis of oligomeric steroids

被引：11

作者：

Cerny, I ^{[1
]}

Budesínsky, M ^{[1
]}

Pouzar, V ^{[1
]}

Drasar, P ^{[1
]}

机构：

[1] Acad Sci Czech Republ, Inst Organ Chem & Biochem, Prague 16610 6, Czech Republic

来源：

COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 2001年 / 66卷 / 06期

关键词：

steroids; active esters; amides; oligoamides; NMR spectroscopy; oligomers;

D O I：

10.1135/cccc20010933

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthesis of linear molecules containing two to four steroid units connected with the amide bonds was developed. As a repeating unit, 3 beta -hydroxyandrost-5-ene-17 beta -carboxylic acid (etienic acid) was used. An active ester of this acid with N-hydroxysuccinimide and its 3-azido analogue were prepared-and methods for the preparation of higher oligomers were studied.

引用

页码：933 / 946

页数：14

共 12 条

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