European guidance for the diagnosis and management of osteoporosis in postmenopausal women

被引:102
作者
Kanis, J. A. [1 ,2 ]
Cooper, C. [3 ,4 ]
Rizzoli, R. [5 ,6 ]
Reginster, J. -Y. [7 ,8 ]
机构
[1] Univ Sheffield, Sch Med, Ctr Metab Bone Dis, Beech Hill Rd, Sheffield S10 2RX, S Yorkshire, England
[2] Australian Catholic Univ, Mary McKillop Hlth Inst, Melbourne, Vic, Australia
[3] Univ Southampton, MRC Lifecourse Epidemiol Unit, Southampton, Hants, England
[4] Univ Oxford, NIHR Musculoskeletal Biomed Res Unit, Oxford, England
[5] Univ Hosp, Geneva, Switzerland
[6] Fac Med Geneva, Geneva, Switzerland
[7] Univ Liege, Dept Publ Hlth Epidemiol & Hlth Econ, Liege, Belgium
[8] King Saud Univ, Coll Sci, Biochem Dept, Prince Mutaib Chair Biomarkers Osteoporosis, Riyadh, Saudi Arabia
关键词
Bone mineral density; Diagnosis of osteoporosis; Fracture risk assessment; FRAX; Health economics; Treatment of osteoporosis; BONE-MINERAL DENSITY; VERTEBRAL FRACTURE RISK; ESTROGEN PLUS PROGESTIN; VITAMIN-D SUPPLEMENTATION; INCREASED CARDIOVASCULAR RISKS; HEALTH TECHNOLOGY-ASSESSMENT; HORMONE REPLACEMENT THERAPY; ZOLEDRONIC ACID TREATMENT; MONTHLY ORAL IBANDRONATE; LIAISON SERVICE MODELS;
D O I
10.1007/s00198-018-4704-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Guidance is provided in a European setting on the assessment and treatment of postmenopausal women at risk from fractures due to osteoporosis.IntroductionThe International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2013. This manuscript updates these in a European setting.MethodsSystematic reviews were updated.ResultsThe following areas are reviewed: the role of bone mineral density measurement for the diagnosis of osteoporosis and assessment of fracture risk; general and pharmacological management of osteoporosis; monitoring of treatment; assessment of fracture risk; case-finding strategies; investigation of patients; health economics of treatment. The update includes new information on the evaluation of bone microstructure evaluation in facture risk assessment, the role of FRAX (R) and Fracture Liaison Services in secondary fracture prevention, long-term effects on fracture risk of dietary intakes, and increased fracture risk on stopping drug treatment.ConclusionsA platform is provided on which specific guidelines can be developed for national use.
引用
收藏
页码:3 / 44
页数:42
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