Nyamuragira (Virunga chain, D. R. Congo) is among Africa's most active volcanoes, but direct observations of its eruptions are rare. From 1978-2002 the Total Ozone Mapping Spectrometer (TOMS) instruments measured SO2 emissions during each of Nyamuragira's 13 most recent eruptions. Due to continuous co-eruptive SO2 degassing, estimating the total atmospheric SO2 loading resulting from eruptions of Nyamuragira is not straightforward. Using TOMS SO2 plume cross-sections and model wind profiles we derive eruptive SO2 fluxes and SO2 loss rates for emissions on 19 October 1998 and 6 February 2001, giving peak SO2 fluxes of 0.21 and 0.74 Tg day(-1) respectively and loss rates of similar to10(-6) -10(-5) s(-1). Based on current data, time-averaged SO2 emission rates at Nyamuragira are comparable to persistent emitters ( Etna, Kilauea), but eruptive fluxes at Nyamuragira are much higher. Considering the alkaline composition of Virunga lavas, eruptive CO2 fluxes could be seven times the SO2 flux.