Helicobacter pylori infection in children

Knowledge about Helicobacter pylori infection in children continues to advance. While its prevalence appears to be falling in developed countries, it remains a major problem in developing nations. Its transmission pathway remains highly controversial. it has not yet been definitively elucidated, although the oral-oral route seems most probable. Infection is most often intrafamilial. Risk factors for infection are associated with low socioeconomic level, including overcrowding, unhygienic conditions, sharing beds in childhood, low maternal educational level. Infection in children differs from that in adults in three respects: symptoms, endoscopic appearance of the gastric mucosa, and histologic appearance of lesions. No study has established a clear association between recurrent abdominal pain and H. pylori infection. Nonetheless, in proven infections, recurrent abdominal pain is the most common marker. More recently, an association has been reported between H. pylori infection and iron deficiency anemia.