Preparation of methyl (1R,2S,5S)- and (1S,2R,5R)-2-amino-5-tert-butyl-cyclopentane-l-carboxylates by parallel kinetic resolution of methyl (RS)-5-tert-butyl-cyclopentene-l-carboxylate

被引：43

作者：

Davies, SG

Díez, D

El Hammouni, MM

Garner, AC

Garrido, NM

Long, MJC

Morrison, RM

Smith, AD

Sweet, MJ

Witheya, JCM

机构：

[1] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England

[2] Univ Salamanca, Dept Quim Organ, E-37008 Salamanca, Spain

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 19期

关键词：

D O I：

10.1039/b308855c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Comparison of the kinetic and parallel kinetic resolutions of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate allows for the efficient synthesis of both (1R,2S,5S)- and (1S,2R,5R)-enantiomers of methyl 2-amino-5-tert-butyl-cyclopentane-1-carboxylate.

引用

页码：2410 / 2411

页数：2

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[21] CISPENTACIN, A NEW ANTIFUNGAL ANTIBIOTIC .2. INVITRO AND INVIVO ANTIFUNGAL ACTIVITIES [J].