Preparation of methyl (1R,2S,5S)- and (1S,2R,5R)-2-amino-5-tert-butyl-cyclopentane-l-carboxylates by parallel kinetic resolution of methyl (RS)-5-tert-butyl-cyclopentene-l-carboxylate

被引：43
作者：
Davies, SG
Díez, D
El Hammouni, MM
Garner, AC
Garrido, NM
Long, MJC
Morrison, RM
Smith, AD
Sweet, MJ
Witheya, JCM
机构：
[1] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England
[2] Univ Salamanca, Dept Quim Organ, E-37008 Salamanca, Spain
来源：
CHEMICAL COMMUNICATIONS | 2003年 / 19期
关键词：
D O I：
10.1039/b308855c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Comparison of the kinetic and parallel kinetic resolutions of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate allows for the efficient synthesis of both (1R,2S,5S)- and (1S,2R,5R)-enantiomers of methyl 2-amino-5-tert-butyl-cyclopentane-1-carboxylate.
引用
收藏
页码：2410 / 2411
页数：2
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