Comparative analysis of condom lubricants on pre & post-coital vaginal swabs using AccuTOF-DART

被引：17
作者：
Proni, Gloria [1 ]
Cohen, Peter [2 ]
Huggins, Lesley-Ann [1 ]
Nesnas, Nasri [2 ]
机构：
[1] CUNY, John Jay Coll Criminal Justice, Dept Sci, 524 West 59th St,5-66-12 NB, New York, NY 10019 USA
[2] Florida Inst Technol, Dept Chem, 150 W Univ Blvd,323 Olin Phys Sci Bldg, Melbourne, FL 32901 USA
来源：
FORENSIC SCIENCE INTERNATIONAL | 2017年 / 280卷
关键词：
Forensic science; Nonoxynol; Sexual assault; Pre- and post-coitus samples; Direct Analysis in Real Time Mass; Spectrometry; Time of flight; MASS-SPECTROMETRY; FORENSIC ANALYSIS; PERSONAL LUBRICANTS; NONOXYNOL-9; CHROMATOGRAPHY; SPECTROSCOPY;
D O I：
10.1016/j.forsciint.2017.09.005
中图分类号：
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号：
0301 ; 10 ;
摘要：
In this study we demonstrate the use of Direct Analysis in Real Time Mass Spectrometry (DART) as a powerful tool for detection of nonoxynol in vaginal fluid post contact with a condom, enabling rapid tracing and added evidences in sexual assault crimes. Vaginal fluid was sampled using cotton swabs and glass rods and measured directly with DART. Sample preparation using water, hexane, methanol, and dichloromethane extraction, was explored for comparison and optimization of signals. Nonoxynol was detected up to eight hours after sampling. Optimal sampling conditions and mass spectrometry parameters are reported and discussed. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码：87 / 94
页数：8
相关论文
共 13 条
[1]   A SIMPLE, SENSITIVE ASSAY FOR THE SPERMICIDE NONOXYNOL-9 IN BIOLOGICAL-FLUIDS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].
BECK, GJ ;
KOSSAK, D ;
SAXENA, SJ .
JOURNAL OF PHARMACEUTICAL SCIENCES, 1990, 79 (11) :1029-1031
[2]   Forensic analysis of condom and personal lubricants by capillary electrophoresis [J].
Burger, F ;
Dawson, M ;
Roux, C ;
Maynard, P ;
Doble, P ;
Kirkbride, P .
TALANTA, 2005, 67 (02) :368-376
[3]   Analysis of condom lubricants for forensic casework [J].
Campbell, Gareth P. ;
Gordon, Amanda L. .
JOURNAL OF FORENSIC SCIENCES, 2007, 52 (03) :630-642
[4]   Versatile new ion source for the analysis of materials in open air under ambient conditions [J].
Cody, RB ;
Laramée, JA ;
Durst, HD .
ANALYTICAL CHEMISTRY, 2005, 77 (08) :2297-2302
[5]   In vitro and in vivo - The story of Nonoxynol 9 [J].
Hillier, SL ;
Moench, T ;
Shattock, R ;
Black, R ;
Reichelderfer, P ;
Veronese, F .
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2005, 39 (01) :1-8
[6]  
Hollenbeck TPE, 1999, J FORENSIC SCI, V44, P783
[7]  
Lee GSH, 2001, J FORENSIC SCI, V46, P808
[8]   A protocol for the forensic analysis of condom and personal lubricants found in sexual assault cases [J].
Maynard, P ;
Allwell, K ;
Roux, C ;
Dawson, M ;
Royds, D .
FORENSIC SCIENCE INTERNATIONAL, 2001, 124 (2-3) :140-156
[9]   Detection of the Spermicide Nonoxynol-9 Via GC-MS [J].
Musah, Rabi A. ;
Vuong, Angela L. ;
Henck, Colin ;
Shepard, Jason R. E. .
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2012, 23 (05) :996-999
[10]   Direct analysis in real time mass spectrometry for analysis of sexual assault evidence [J].
Musah, Rabi A. ;
Cody, Robert B. ;
Dane, A. John ;
Vuong, Angela L. ;
Shepard, Jason R. E. .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2012, 26 (09) :1039-1046
12