19-Substituted benzoquinone ansamycin Hsp90 inhibitors: Effects on Hsp90 co-chaperones and Hsp90-Hsf1 complexes in cellular systems

被引:0
|
作者
Drechsel, Derek A. [1 ]
Chang, Chuan-Hsin [1 ]
Kitson, Russell [2 ]
Siegel, David [1 ]
Moody, Christopher J. [2 ]
Ross, David [1 ]
机构
[1] Univ Colorado Anschutz Med Campus, Aurora, CO USA
[2] Univ Nottingham, Nottingham NG7 2RD, England
关键词
D O I
10.1158/1538-7445.AM2014-1791
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1791
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Plant Hsp90 and its Co-Chaperones
    Breiman, Adina
    CURRENT PROTEIN & PEPTIDE SCIENCE, 2014, 15 (03) : 232 - 244
  • [2] Effect of 19-substituted benzoquinone ansamycin Hsp90 inhibitors on Hsp90/Cdc37/co-chaperone complexes and casein kinase 2 (CK2) activity
    Chang, Chuan-Hsin
    Rossi, David
    Siegel, David
    Moody, Christopher J.
    Kitson, Russell
    CANCER RESEARCH, 2015, 75
  • [3] HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation
    Kijima, Toshiki
    Prince, Thomas L.
    Tigue, Megan L.
    Yim, Kendrick H.
    Schwartz, Harvey
    Beebe, Kristin
    Lee, Sunmin
    Budzynski, Marek A.
    Williams, Heinric
    Trepel, Jane B.
    Sistonen, Lea
    Calderwood, Stuart
    Neckers, Len
    SCIENTIFIC REPORTS, 2018, 8
  • [4] Hsp90 and Its Co-Chaperones in Neurodegenerative Diseases
    Bohush, Anastasiia
    Bieganowski, Pawel
    Filipek, Anna
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (20)
  • [5] HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation
    Tigue, Megan L.
    Kijima, Toshiki
    Prince, Thomas L.
    Yim, Kendrick H.
    Schwartz, Harvey
    Beebe, Kristin
    Lee, Sunmin
    Budzynski, Marek A.
    Williams, Heinric
    Trepel, Jane B.
    Sistonen, Lea
    Calderwood, Stuart
    Neckers, Len
    CANCER RESEARCH, 2018, 78 (13)
  • [6] HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation
    Toshiki Kijima
    Thomas L. Prince
    Megan L. Tigue
    Kendrick H. Yim
    Harvey Schwartz
    Kristin Beebe
    Sunmin Lee
    Marek A. Budzynski
    Heinric Williams
    Jane B. Trepel
    Lea Sistonen
    Stuart Calderwood
    Len Neckers
    Scientific Reports, 8
  • [7] Hsp90 and Associated Co-Chaperones of the Malaria Parasite
    Dutta, Tanima
    Singh, Harpreet
    Edkins, Adrienne L.
    Blatch, Gregory L.
    BIOMOLECULES, 2022, 12 (08)
  • [8] Reduction of benzoquinone ansamycin Hsp90 inhibitors by NQO1 generates hydroquinone ansamycins which are more potent Hsp90 inhibitors
    Guo, Wenchang
    Reigan, Philip
    Siegel, David
    Zirrolli, Joseph
    Gustafson, Daniel
    Ross, David
    CANCER RESEARCH, 2006, 66 (08)
  • [9] Observing the Regulation of the Hsp90 Chaperone by Co-Chaperones and Nucleotides
    Tych, Katarzyna M.
    Jahn, Markus
    Girstmair, Hannah
    Hugel, Thorsten
    Buchner, Johannes
    Rief, Matthias
    BIOPHYSICAL JOURNAL, 2021, 120 (03) : 8A - 8A
  • [10] Regulation of insulin receptor expression by Hsp90 and co-chaperones
    Yanagita, Toshihiko
    Nemoto, Takayuki
    Wada, Akihiko
    Murakami, Manabu
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011, 115 : 122P - 122P