Onychomadesis after a hand, foot, and mouth disease outbreak in Spain, 2009

被引:24
作者
Cabrerizo, M. [1 ]
De Miguel, T.
Armada, A. [2 ]
Martinez-Risco, R. [2 ]
Pousa, A. [3 ]
Trallero, G.
机构
[1] Inst Salud Carlos III, Natl Ctr Microbiol, Enterovirus Lab, Dept Virol, Madrid, Spain
[2] Dept Terr Sanidad, Serv Alertas Epidemiol, La Coruna, Spain
[3] Direcc Gen Salud Publ & Planificac, Serv Epidemiol, Santiago De Compostela, Spain
关键词
Enterovirus; genotyping; phylogenetic analysis; NAIL MATRIX ARREST; CHINA;
D O I
10.1017/S0950268810002219
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Few reports exist regarding the association between onychomadesis and an enterovirus infection presenting clinically as hand, foot, and mouth disease (HFMD). In February 2009, an outbreak of HFMD occurred in a Spanish nursery school, followed by onychomadesis 36-69 days later. Twelve of 17 children with HFMD developed nail shedding; enterovirus was detected in stool samples from eight (47%) of the 17. However, in only three of the children could an enterovirus serotype coxsackievirus B1 be identified. The epidemiological results of this study confirm onychomadesis as a complication in HFMD. In future outbreaks, molecular characterization of enterovirus from appropriate clinical samples should be studied.
引用
收藏
页码:1775 / 1778
页数:4
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