Symmetry and dynamics of molecular rotors in amphidynamic molecular crystals

被引：105

作者：

Karlen, Steven D. ^{[1
]}

Reyes, Horacio ^{[1
]}

Taylor, R. E. ^{[1
]}

Khan, Saeed I. ^{[1
]}

Hawthorne, M. Frederick ^{[1
]}

Garcia-Garibay, Miguel A. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2010年 / 107卷 / 34期

关键词：

solid-state NMR; line shape analysis; spin-lattice relaxation; molecular design; crystal engineering; SOLID-STATE DYNAMICS; MACHINES; ROTATION; GYROSCOPES; PHENYLENE; ROTATORS; DIPOLAR; NMR;

D O I：

10.1073/pnas.1008213107

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Rotary biomolecular machines rely on highly symmetric supramolecular structures with rotating units that operate within a densely packed frame of reference, stator, embedded within relatively rigid membranes. The most notable examples are the enzyme FoF1 ATP synthase and the bacterial flagellum, which undergo rotation in steps determined by the symmetries of their rotators and rotating units. Speculating that a precise control of rotational dynamics in rigid environments will be essential for the development of artificial molecular machines, we analyzed the relation between rotational symmetry order and equilibrium rotational dynamics in a set of crystalline molecular gyroscopes with rotators having axial symmetry that ranges from two- to fivefold. The site exchange frequency for these molecules in their closely related crystals at ambient temperature varies by several orders of magnitude, up to ca. 4.46 x 10(8) s(-1).

引用

页码：14973 / 14977

页数：5

共 28 条

[1]

Akutagawa T, 2009, NAT MATER, V8, P342, DOI [10.1038/NMAT2377, 10.1038/nmat2377]

[2] TEMPERATURE-DEPENDENCE OF PB-207 MAS SPECTRA OF SOLID LEAD NITRATE - AN ACCURATE, SENSITIVE THERMOMETER FOR VARIABLE-TEMPERATURE MAS [J].

BIELECKI, A ;

BURUM, DP .

JOURNAL OF MAGNETIC RESONANCE SERIES A, 1995, 116 (02) :215-220

[3] Making molecular machines work [J].

Browne, Wesley R. ;

Feringa, Ben L. .

NATURE NANOTECHNOLOGY, 2006, 1 (01) :25-35

[4] Controlled-Access Hollow Mechanized Silica Nanocontainers [J].

Du, Li ;

Liao, Shijun ;

Khatib, Hussam A. ;

Stoddart, J. Fraser ;

Zink, Jeffrey I. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (42) :15136-15142

[5] How molecules stick together in organic crystals: weak intermolecular interactions [J].

Dunitz, Jack D. ;

Gavezzotti, Angelo .

CHEMICAL SOCIETY REVIEWS, 2009, 38 (09) :2622-2633

[6] Acid-Base Actuation of [c2]Daisy Chains [J].

Fang, Lei ;

Hmadeh, Mohamad ;

Wu, Jishan ;

Olson, Mark A. ;

Spruell, Jason M. ;

Trabolsi, Ali ;

Yang, Ying-Wei ;

Elhabiri, Mourad ;

Albrecht-Gary, Anne-Marie ;

Stoddart, J. Fraser .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (20) :7126-7134

[7] A reversible, unidirectional molecular rotary motor driven by chemical energy [J].

Fletcher, SP ;

Dumur, F ;

Pollard, MM ;

Feringa, BL .

SCIENCE, 2005, 310 (5745) :80-82

[8]

Fyfe C.A., 1983, SOLID STATE NMR CHEM

[9] Crystalline molecular machines: Encoding supramolecular dynamics into molecular structure [J].

Garcia-Garibay, MA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (31) :10771-10776

[10] Engineering Crystal Packing and Internal Dynamics in Molecular Gyroscopes by Refining their Components. Fast Exchange of a Phenylene Rotator by 2H NMR [J].

Garcia-Garibay, Miguel A. ;

Godinez, Carlos E. .

CRYSTAL GROWTH & DESIGN, 2009, 9 (07) :3124-3128

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