Aging research in India

被引:3
作者
Ashok, BT
Ali, R
机构
[1] New York Med Coll, Dept Microbiol & Immunol, Valhalla, NY 10595 USA
[2] Aligarh Muslim Univ, JN Med Coll, Dept Biochem, Aligarh 202002, Uttar Pradesh, India
关键词
aging; Ayurveda; free radicals; DNA damage; India;
D O I
10.1016/S0531-5565(03)00089-5
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Research on aging in India has been well documented since ancient times. As way back as 3000-1500 BC, the Indian medical system of Ayurveda was used as a means for the prevention of the effects of aging and generation of disease in organs or the whole organism, respectively. In recent years, the focus has been demographic studies on different aspects of aging and has been in isolation. Molecular aspects of aging have been addressed only by a few groups of scientists which has focused on regulation of gene expression, DNA damage and repair, development of immunochemical reagents to detect oxidative DNA damage and assessing the levels of circulating antibodies to reactive oxygen species modified DNA (ROS-DNA), etc. This review aims to recapitulate various research studies on aging since 3000 BC to date. (C) 2003 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:597 / 603
页数:7
相关论文
共 84 条
[1]  
AHUJA B, 1995, THESIS U DELHI
[2]  
Arora V K, 1989, J Assoc Physicians India, V37, P205
[3]   The aging paradox: free radical theory of aging [J].
Ashok, BT ;
Ali, R .
EXPERIMENTAL GERONTOLOGY, 1999, 34 (03) :293-303
[4]   Immunochemical detection of oxidative DNA damage in cancer and aging using anti-reactive oxygen species modified DNA monoclonal antibody [J].
Ashok, BT ;
Ahmad, J ;
Ali, R .
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 1998, 30 (12) :1367-1377
[5]  
Ashok BT, 1997, BIOCHEM MOL BIOL INT, V43, P1219
[6]   Binding of circulating antibodies to reactive oxygen species modified-DNA and detecting DNA damage by a monoclonal antibody probe [J].
Ashok, BT ;
Ali, R .
MECHANISMS OF AGEING AND DEVELOPMENT, 1998, 103 (01) :69-80
[7]  
Ashok BT, 1998, INT J CANCER, V78, P404, DOI 10.1002/(SICI)1097-0215(19981109)78:4<404::AID-IJC2>3.0.CO
[8]  
2-Y
[9]  
BALAKRISHNAN S, 1987, INDIAN PRACT, V11, P401
[10]  
Bambawale U., 1996, AGEING INDIAN PERSPE, P298