Neutron scattering in the biological sciences: progress and prospects

被引：51

作者：

Ashkar, Rana ^{[1
]}

Bilheux, Hassina Z. ^{[2
]}

Bordallo, Heliosa ^{[3
]}

Briber, Robert ^{[4
]}

Callaway, David J. E. ^{[5
]}

Cheng, Xiaolin ^{[6
]}

Chu, Xiang-Qiang ^{[7
]}

Curtis, Joseph E. ^{[8
]}

Dadmun, Mark ^{[9
]}

Fenimore, Paul ^{[10
]}

Fushman, David ^{[11
]}

Gabel, Frank ^{[12
]}

Gupta, Kushol ^{[13
]}

Herberle, Frederick ^{[2
]}

Heinrich, Frank ^{[8
,14
]}

Hong, Liang ^{[15
]}

Katsaras, John ^{[16
,17
]}

Kelman, Zvi ^{[18
,19
]}

Kharlampieva, Eugenia ^{[20
]}

Kneller, Gerald R. ^{[21
]}

Kovalevsky, Andrey ^{[22
]}

Krueger, Susan ^{[8
]}

Langan, Paul ^{[2
]}

Lieberman, Raquel ^{[23
]}

Liu, Yun ^{[8
]}

Losche, Mathias ^{[14
]}

Lyman, Edward ^{[24
]}

Mao, Yimin ^{[8
]}

Marino, John ^{[18
,19
]}

Mattos, Carla ^{[25
]}

Meilleur, Flora ^{[2
,26
]}

Moody, Peter ^{[27
]}

Nickels, Jonathan D. ^{[28
]}

O'Dell, William B. ^{[18
,19
]}

O'Neill, Hugh ^{[2
]}

Perez-Salas, Ursula ^{[29
]}

Peters, Judith ^{[30
]}

Petridis, Loukas ^{[31
]}

Sokolov, Alexei P. ^{[9
]}

Stanley, Christopher ^{[2
]}

Wagner, Norman ^{[32
]}

Weinrich, Michael ^{[8
]}

Weiss, Kevin ^{[2
]}

Wymore, Troy ^{[34
]}

Zhang, Yang ^{[35
]}

Smith, Jeremy C. ^{[33
]}

机构：

[1] Virginia Polytech Inst & State Univ, Dept Phys, 850 West Campus Dr, Blacksburg, VA 24061 USA

[2] Oak Ridge Natl Lab, Neutron Sci Directorate, 1 Bethel Valley Rd, Oak Ridge, TN 37831 USA

[3] Niels Bohr Inst, DK-2100 Copenhagen, Denmark

[4] Univ Maryland, Mat Sci & Engineeering, 1109 Chem & Nucl Engn Bldg, College Pk, MD 20742 USA

[5] CUNY City Coll, Dept Chem & Biochem, 160 Convent Ave, New York, NY 10031 USA

[6] Ohio State Univ, Coll Pharm, Dept Med Chem & Pharmacognosy, 642 Riffe Bldg, Columbus, OH 43210 USA

[7] Grad Sch China Acad Engn Phys, Beijing 100193, Peoples R China

[8] NIST, NIST Ctr Neutron Res, 100 Bur Dr,Mail Stop 6102, Gaithersburg, MD 20899 USA

[9] Univ Tennessee, Dept Chem, Knoxville, TN 37996 USA

[10] Los Alamos Natl Lab, Los Alamos, NM 87545 USA

[11] Univ Maryland, Ctr Biomol Struct & Org, Dept Chem & Biochem, College Pk, MD 20742 USA

[12] Univ Grenoble Alpes, CNRS, CEA, Inst Laue Langevin,IBS, F-38042 Grenoble, France

[13] Univ Penn, Perelman Sch Med, Dept Biochem & Biophys, Philadelphia, PA 19104 USA

[14] Carnegie Mellon Univ, Dept Phys, Pittsburgh, PA 15213 USA

[15] Shanghai Jiao Tong Univ, Inst Nat Sci, Dept Phys & Astron, Shanghai 200240, Peoples R China

[16] Oak Ridge Natl Lab, Neutron Scattering Sci Div, Oak Ridge, TN 37831 USA

[17] CNR, Canadian Neutron Beam Ctr, Chalk River, ON, Canada

[18] NIST, Inst Biosci & Biotechnol Res, Rockville, MD 20850 USA

[19] Univ Maryland, Rockville, MD 20850 USA

[20] Univ Alabama Birmingham, Dept Chem, 901 14th St South, Birmingham, AL 35294 USA

[21] Univ Orleans, CNRS, Ctr Biophys Mol, Ave Parc Floral, Orleans, France

[22] Oak Ridge Natl Lab, Biol & Soft Matter Div, Oak Ridge, TN 37831 USA

[23] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA

[24] Univ Delaware, Dept Phys & Astrophys, Newark, DE 19716 USA

[25] Northeastern Univ, Dept Chem & Chem Biol, Boston, MA 02115 USA

[26] North Carolina State Univ, Dept Mol & Struct Biochem, Raleigh, NC 27695 USA

[27] Univ Leicester, Leicester Inst Struct & Chem Biol, Dept Mol & Cell Biol, Leicester LE1 9HN, Leics, England

[28] Univ Cincinnati, Dept Chem & Environm Engn, Cincinnati, OH 45221 USA

[29] Univ Illinois, Chicago, IL USA

[30] Univ Grenoble Alpes, Inst Laue Langevin, LiPhy, Grenoble, France

[31] Oak Ridge Natl Lab, Biosci Div, UT ORNL Ctr Mol Biophys, 1 Bethel Valley Rd, Oak Ridge, TN 37831 USA

[32] Univ Delaware, Ctr Neutron Sci, Dept Chem & Biomol Engn, Newark, DE 19716 USA

[33] Univ Tennessee, Dept Biochem Cellular & Mol Biol, Knoxville, TN 37996 USA

[34] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

[35] Univ Illinois, Beckman Inst Adv Sci & Technol, Dept Nucl Plasma & Radiol Engn, Dept Mat Sci & Engn,Dept Elect & Comp Engn, Urbana, IL 61801 USA

来源：

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY | 2018年 / 74卷

基金：

美国国家科学基金会; 英国生物技术与生命科学研究理事会;

关键词：

neutron scattering; biological systems; structure and dynamics; HIGH-RESOLUTION NEUTRON; SMALL-ANGLE SCATTERING; MOLECULAR-DYNAMICS SIMULATIONS; RAY CRYSTALLOGRAPHIC ANALYSIS; CARBONIC-ANHYDRASE II; PROTEIN DOMAIN MOTION; D-XYLOSE ISOMERASE; X-RAY; CRYSTAL-STRUCTURE; ESCHERICHIA-COLI;

D O I：

10.1107/S2059798318017503

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The scattering of neutrons can be used to provide information on the structure and dynamics of biological systems on multiple length and time scales. Pursuant to a National Science Foundation-funded workshop in February 2018, recent developments in this field are reviewed here, as well as future prospects that can be expected given recent advances in sources, instrumentation and computational power and methods. Crystallography, solution scattering, dynamics, membranes, labeling and imaging are examined. For the extraction of maximum information, the incorporation of judicious specific deuterium labeling, the integration of several types of experiment, and interpretation using high-performance computer simulation models are often found to be particularly powerful.

引用

页码：1129 / 1168

页数：40

共 373 条

[91] Neutron Structure of Human Carbonic Anhydrase II: Implications for Proton Transfer
Fisher, S. Zoe
Kovalevsky, Andrey Y.
Domsic, John F.
Mustyakimov, Marat
McKenna, Robert
Silverman, David N.
Langan, Paul A.
[J]. BIOCHEMISTRY, 2010, 49 (03) : 415 - 421
[92] An evaluation review of the prediction of protonation states in proteins versus crystallographic experiment
Fisher, Stuart J.
Wilkinson, James
Henchman, Richard H.
Helliwell, John R.
[J]. CRYSTALLOGRAPHY REVIEWS, 2009, 15 (04) : 231 - 259
[93] Fitter J., 2006, P1
[94] Editorial on the Topical Issue "Neutron Biological Physics"
Fragneto, Giovanna
Gabel, Frank
[J]. EUROPEAN PHYSICAL JOURNAL E, 2013, 36 (07)
[95] The role of momentum transfer during incoherent neutron scattering is explained by the energy landscape model
Frauenfelder, Hans
Young, Robert D.
Fenimore, Paul W.
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (20) : 5130 - 5135
[96] A unified model of protein dynamics
Frauenfelder, Hans
Chen, Guo
Berendzen, Joel
Fenimore, Paul W.
Jansson, Helen
McMahon, Benjamin H.
Stroe, Izabela R.
Swenson, Jan
Young, Robert D.
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (13) : 5129 - 5134
[97] Efficient segmental isotope labeling of multi-domain proteins using Sortase A
Freiburger, Lee
Sonntag, Miriam
Hennig, Janosch
Li, Jian
Zou, Peijian
Sattler, Michael
[J]. JOURNAL OF BIOMOLECULAR NMR, 2015, 63 (01) : 1 - 8
[98] Bioprocess Control in Microscale: Scalable Fermentations in Disposable and User-Friendly Microfluidic Systems
Funke, Matthias
Buchenauer, Andreas
Mokwa, Wilfried
Kluge, Stefanie
Hein, Lea
Mueller, Carsten
Kensy, Frank
Buechs, Jochen
[J]. MICROBIAL CELL FACTORIES, 2010, 9
[99] Microfluidic BioLector-Microfluidic Bioprocess Control in Microtiter Plates
Funke, Matthias
Buchenauer, Andreas
Schnakenberg, Uwe
Mokwa, Wilfried
Diederichs, Sylvia
Mertens, Alan
Mueller, Carsten
Kensy, Frank
Buechs, Jochen
[J]. BIOTECHNOLOGY AND BIOENGINEERING, 2010, 107 (03) : 497 - 505
[100] Neutron radiography of a root growing in soil with vanadium
Furukawa, J
Nakanishi, TM
Matsubayashi, H
[J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1999, 424 (01) : 116 - 121

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