New Insight Into the Mechanisms of Fast-Acting Antidepressants: What We Learn From Scopolamine

被引:6
作者
Anacker, Christoph [1 ]
机构
[1] Columbia Univ, Dept Psychiat, New York State Psychiat Inst, Div Integrat Neurosci, 40 Haven Ave,Room 721, New York, NY 10032 USA
关键词
VAL66MET POLYMORPHISM; EFFICACY;
D O I
10.1016/j.biopsych.2017.11.001
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:E5 / E7
页数:3
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共 10 条
[1]   Adult hippocampal neurogenesis and cognitive flexibility - linking memory and mood [J].
Anacker, Christoph ;
Hen, Rene .
NATURE REVIEWS NEUROSCIENCE, 2017, 18 (06) :335-346
[2]   Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior [J].
Chen, Zhe-Yu ;
Jing, Deqiang ;
Bath, Kevin G. ;
Ieraci, Alessandro ;
Khan, Tanvir ;
Siao, Chia-Jen ;
Herrera, Daniel G. ;
Toth, Miklos ;
Yang, Chingwen ;
McEwen, Bruce S. ;
Hempstead, Barbara L. ;
Lee, Francis S. .
SCIENCE, 2006, 314 (5796) :140-143
[3]   Antidepressant efficacy of the antimuscarinic drug scopolamine - A randomized, placebo-controlled clinical trial [J].
Furey, Maura L. ;
Drevets, Wayne C. .
ARCHIVES OF GENERAL PSYCHIATRY, 2006, 63 (10) :1121-1129
[4]  
Ghosal S, BIOL PSYCHIAT, V83, P29
[5]   Brain-Derived Neurotrophic Factor Val66Met Polymorphism and Antidepressant Efficacy of Ketamine in Depressed Patients [J].
Laje, Gonzalo ;
Lally, Niall ;
Mathews, Daniel ;
Brutsche, Nancy ;
Chemerinski, Anat ;
Akula, Nirmala ;
Kelmendi, Benjamin ;
Simen, Arthur ;
McMahon, Francis J. ;
Sanacora, Gerard ;
Zarate, Carlos, Jr. .
BIOLOGICAL PSYCHIATRY, 2012, 72 (11) :E27-E28
[6]   mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists [J].
Li, Nanxin ;
Lee, Boyoung ;
Liu, Rong-Jian ;
Banasr, Mounira ;
Dwyer, Jason M. ;
Iwata, Masaaki ;
Li, Xiao-Yuan ;
Aghajanian, George ;
Duman, Ronald S. .
SCIENCE, 2010, 329 (5994) :959-964
[7]   Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors [J].
Navarria, Andrea ;
Wohleb, Eric S. ;
Voleti, Bhavya ;
Ota, Krikie T. ;
Dutheil, Sophie ;
Lepack, Ashley E. ;
Dwyer, Jason M. ;
Fuchikami, Manabu ;
Becker, Astrid ;
Drago, Filippo ;
Duman, Ronald S. .
NEUROBIOLOGY OF DISEASE, 2015, 82 :254-261
[8]   A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders [J].
Sanacora, Gerard ;
Frye, Mark A. ;
McDonald, William ;
Mathew, Sanjay J. ;
Turner, Mason S. ;
Schatzberg, Alan F. ;
Summergrad, Paul ;
Nemeroff, Charles B. .
JAMA PSYCHIATRY, 2017, 74 (04) :399-405
[9]   Scopolamine Rapidly Increases Mammalian Target of Rapamycin Complex 1 Signaling, Synaptogenesis, and Antidepressant Behavioral Responses [J].
Voleti, Bhavya ;
Navarria, Andrea ;
Liu, Rong-Jian ;
Banasr, Mounira ;
Li, Nanxin ;
Terwilliger, Rose ;
Sanacora, Gerard ;
Eid, Tore ;
Aghajanian, George ;
Duman, Ronald S. .
BIOLOGICAL PSYCHIATRY, 2013, 74 (10) :742-749
[10]   GABA interneurons mediate the rapid antidepressant-like effects of scopolamine [J].
Wohleb, Eric S. ;
Wu, Min ;
Gerhard, Danielle M. ;
Taylor, Seth R. ;
Picciotto, Marina R. ;
Alreja, Meenakshi ;
Duman, Ronald S. .
JOURNAL OF CLINICAL INVESTIGATION, 2016, 126 (07) :2482-2494