Hematopoietic development: a balancing act

被引:158
作者
Cantor, AB [1 ]
Orkin, SH [1 ]
机构
[1] Childrens Hosp, Div Hematol Oncol, Boston, MA 02115 USA
关键词
D O I
10.1016/S0959-437X(00)00226-4
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Over the past year, significant new insights have been gained in our understanding of the lineage determination of red blood cells. In particular, evidence has emerged demonstrating that cross-antagonism of lineage-specific transcription factors plays an important role in determining cell phenotype by actively repressing alternate lineage gene programs.
引用
收藏
页码:513 / 519
页数:7
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