Site specific protein immobilization into structured polymer brushes prepared by AFM lithography

被引：23

作者：

Wagner, Hendrik ^{[2
]}

Li, Yong ^{[1
,3
]}

Hirtz, Michael ^{[4
,5
]}

Chi, Lifeng ^{[1
,3
]}

Fuchs, Harald ^{[1
,3
]}

Studer, Armido ^{[2
]}

机构：

[1] Univ Munster, Inst Phys, D-48149 Munster, Germany

[2] Univ Munster, Inst Organ Chem, D-48149 Munster, Germany

[3] Ctr Nanotechnol CeNTech, D-48149 Munster, Germany

[4] Karlsruhe Inst Technol, Inst Nanotechnol, D-76131 Karlsruhe, Germany

[5] Karlsruhe Inst Technol, KNMF, D-76131 Karlsruhe, Germany

来源：

SOFT MATTER | 2011年 / 7卷 / 21期

关键词：

DIP-PEN NANOLITHOGRAPHY; SURFACE-INITIATED POLYMERIZATION; RADICAL POLYMERIZATION; METHACRYLATE) BRUSHES; NANOARRAYS; CHEMISTRY; PATTERNS; ADHESION; BEHAVIOR; GLYCOL);

D O I：

10.1039/c1sm06013a

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Protein immobilization into structured polymer brushes was achieved by AFM lithography. Dense polystyrene brushes with thicknesses larger than 40 nm show protein repellent properties whereas brushes with thicknesses smaller than 20 nm show the expected known protein adsorption behavior. Multi tip AFM lithography allows for large surface area patterning.

引用

页码：9854 / 9858

页数：5

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