Homocysteine and folate status in an era of folic acid fortification: Balancing benefits, risks, and B-vitamins

被引:5
作者
Ueland, Per Magne [1 ]
Hustad, Steinar [2 ]
机构
[1] Univ Bergen, Inst Med, Pharmacol Sect, Bergen, Norway
[2] Haukeland Hosp, Hormone Lab, N-5021 Bergen, Norway
关键词
D O I
10.1373/clinchem.2008.103218
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
引用
收藏
页码:779 / 781
页数:3
相关论文
共 30 条
[1]  
Baily LB, 1998, NUTR REV, V56, P294, DOI 10.1111/j.1753-4887.1998.tb01662.x
[2]   Very low oral doses of vitamin B-12 increase serum concentrations in elderly subjects with food-bound vitamin B-12 malabsorption [J].
Blacher, Jacques ;
Czernichow, Sebastien ;
Raphael, Mathilde ;
Roussel, Christophe ;
Chadefaux-Vekemans, Bernadette ;
Morineau, Gilles ;
Giraudier, Stephane ;
Tibi, Annick ;
Henry, Olivier ;
Vayssiere, Michel ;
Oudjhani, Moussa ;
Nadai, Sophie ;
Vincent, Jean-Pierre ;
Bodak, Alexandre ;
Di Menza, Claude ;
Menard, Joel ;
Zittoun, Jacqueline ;
Ducimetiere, Pierre .
JOURNAL OF NUTRITION, 2007, 137 (02) :373-378
[3]   Folic acid intake from fortification in United States exceeds predictions [J].
Choumenkovitch, SF ;
Selhub, J ;
Wilson, PWF ;
Rader, JI ;
Rosenberg, IH ;
Jacques, PF .
JOURNAL OF NUTRITION, 2002, 132 (09) :2792-2798
[4]   Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials [J].
Clarke, R ;
Frost, C ;
Sherliker, P ;
Lewington, S ;
Collins, R ;
Brattstrom, L ;
Brouwer, I ;
van Dusseldorp, M ;
Steegers-Theunissen, RPM ;
Cuskelly, G ;
Ward, M ;
McNulty, H ;
Scott, J ;
den Heijer, M ;
Blom, H ;
van der Put, N ;
Shorah, CJ ;
Malinow, MR ;
McMahon, M ;
Tobert, J ;
Kush, D ;
Joosten, E ;
Riezier, R ;
Pietrzik, K ;
Dierkes, J ;
Bronstrup, A ;
Jacques, P ;
Mason, J ;
Rosenberg, I ;
Thambyrajah, J ;
Landray, M ;
Townend, J ;
Wheeler, D ;
Ubbink, J ;
van Oort, F ;
Melse-Boonstra, A ;
Verhoef, P ;
Woodside, JV ;
Yarnell, J ;
Young, IS ;
Evans, AE ;
Wald, D ;
Law, M ;
Wald, N .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2005, 82 (04) :806-812
[5]  
Durga J, 2007, J NUTR HEALTH AGING, V11, P320
[6]   Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency -: A dose-finding trial [J].
Eussen, SJPM ;
de Groot, CPGM ;
Clarke, R ;
Schneede, J ;
Ueland, PM ;
Hoefnagels, WHL ;
van Staveren, WA .
ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (10) :1167-1172
[7]   Trends in serum folate, RBC folate, and circulating total homocysteine concentrations in the United States: Analysis of data from National Health and Nutrition Examination Surveys, 1988-1994, 1999-2000, and 2001-2002 [J].
Ganji, V ;
Kafai, MR .
JOURNAL OF NUTRITION, 2006, 136 (01) :153-158
[8]   Vitamin B12 deficiency is the dominant nutritional cause of hyperhomocysteinemia in a folic acid-fortified population [J].
Green, R ;
Miller, JW .
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2005, 43 (10) :1048-1051
[9]   Hyperhomocysteinaemia: A critical review of old and new aspects [J].
Herrmann, Wolfgang ;
Herrmann, Markus ;
Obeid, Rima .
CURRENT DRUG METABOLISM, 2007, 8 (01) :17-31
[10]   Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C->T genotypes and B-vitamin status in a large-scale epidemiological study [J].
Holm, Pal I. ;
Hustad, Steinar ;
Ueland, Per Magne ;
Vollset, Stein Emil ;
Grotmol, Tom ;
Schneede, Jorn .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (04) :1535-1541