Persistent lipid abnormalities in patients with hypertension and dyslipidemia treated with statins: results of the Portuguese hypertensive subpopulation of the Dyslipidemia International Study (DYSIS)

被引:6
作者
Silva, Pedro M. [1 ]
Cardoso, Salvador M. [2 ]
Ferreira, Antonio M. [3 ]
机构
[1] Hosp Santa Marta, Internal Med 4, Lisbon, Portugal
[2] Univ Coimbra, Dept Epidemiol, Coimbra, Portugal
[3] Hosp Santa Cruz, Western Lisbon Hosp Ctr, Cardiol, Carnaxide, Portugal
关键词
Cardiovascular disease; dyslipidemia; HMG-CoA; hypertension; simvastatin; statins; RISK-FACTORS; CARDIOVASCULAR RISK; BLOOD-PRESSURE; HEART-DISEASE; LDL-CHOLESTEROL; PREVENTION; GUIDELINES; STROKE; COUNTRIES; ASSOCIATION;
D O I
10.3109/10641963.2014.913605
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
This study aimed to assess the treatment patterns and prevalence of persistent lipid abnormalities in Portuguese hypertensive patients concomitantly treated with statins. Only 25% of the 656 hypertensive patients achieved the blood pressure goals in use during the study period. Similarly, only 33% and 37% attained the recommended levels of total cholesterol <4.5 mmol/L and LDL cholesterol <2.5 mmol/L, respectively. Relatively low doses of medium potency statins were the mainstay of therapy. There seems to be considerable room for improvement through the use of more potent statins, dose up-titration, and/or addition of other lipid-modifying therapies.
引用
收藏
页码:116 / 121
页数:6
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