Nitrofurantoin-induced lung disease:: about two cases

被引：2

作者：

Mrozek, N. ^{[1
]}

Delevaux, I. ^{[1
]}

Legendre, M. ^{[1
]}

Andre, M. ^{[1
]}

Trouillier, S. ^{[1
]}

Voinchet, H. ^{[1
]}

Aumaitre, O. ^{[1
]}

机构：

[1] CHU Gabriel Montpied, Serv Med Interne, F-63003 Clermont Ferrand 01, France

来源：

REVUE DE MEDECINE INTERNE | 2008年 / 29卷 / 02期

关键词：

nitrofurantoin; interstitial lung disease;

D O I：

10.1016/j.revmed.2007.06.016

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction. - Nitrofurantoin is commonly used in the treatment of urinary tract infection and may cause a potential severe complication: interstitial lung diseases. Case report. - A 78-year-old and an 87-year-old woman treated with nitrofurantoin since respectively 10 months and 6 years developped cough and dyspnea. Antibiotics were ineffective and interstitial lung disease was found. Nitrofurantoin's stopping allowed a clinical and radiological improvement. Conclusion. - A good medical supervision is important when nitrofurantoine is prescribed for a long time. The treatment has to be stopped when respiratory symptoms appear to allow an improvment of the symptoms. (C) 2007 Elsevier Masson SAS.

引用

页码：149 / 151

页数：3

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