Differential diagnosis by unenhanced FLAIR T2-weighted magnetic resonance images between solitary high grade gliomas and cerebral metastases appearing as contrast-enhancing cortico-subcortical lesions

被引：20
作者：
Muccio, Carmine Franco [1 ]
Tarantino, Annachiara [2 ,3 ]
Esposito, Gennaro [1 ]
Cerase, Alfonso [4 ]
机构：
[1] Azienda Osped Rilievo Nazl Gaetano Rummo, Dept Neurosci, Unit Neuroradiol, I-82100 Benevento, Italy
[2] IRCCS, Ist Neurol Mediterraneo Neuromed, Dept Diagnost Imaging, Unit Expt & Funct Neuroradiol, Pozzilli, Isernia, Italy
[3] Ctr DITAR Srl Radiol Diagnost Med, Benevento, Italy
[4] Azienda Osped Univ Senese, Policlin Santa Maria Scotte, Dept Neurosci, Unit NINT Neuroimaging & Neurointervent, Siena, Italy
来源：
JOURNAL OF NEURO-ONCOLOGY | 2011年 / 103卷 / 03期
关键词：
Cerebral metastases; Fluid-attenuated inversion recovery; Gadolinium-enhancement; High-grade gliomas; BRAIN METASTASES; INTRACRANIAL TUMORS; MR; PERFUSION; SEQUENCES; ECHO; GLIOBLASTOMAS; SPECTROSCOPY; NEOPLASMS; DIFFUSION;
D O I：
10.1007/s11060-010-0454-8
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The aim was to assess the value of unenhanced fluid-attenuated inversion recovery T2-weighted sequences (FLAIR-T2) in the differential diagnosis between solitary high-grade gliomas (HGG) and cerebral metastases (CM) appearing as contrast-enhancing cortico-subcortical lesions of the brain. In 69 patients with a contrast-enhancing cortico-subcortical brain lesion (43 HGG, and 26 CM), unenhanced FLAIR-T2 and gadolinium-enhanced FLAIR T1-weighted (Gd-FLAIR-T1) axial images have been reviewed for the involvement of the cortex adjacent to the contrast-enhancing lesion. In 27 (62.79%) out of 43 HGG, and 3 (11.53%) out of 26 CM, the cortex adjacent to the contrast-enhancing lesion showed high signal intensity on unenhanced FLAIR-T2 without enhancement at Gd-FLAIR-T1. Fischer's exact probability test was P = 0.0003 when applied to HGG versus CM categories, indicating a significant difference. The high signal intensity on unenhanced FLAIR-T2 without gadolinium-enhancement of the cortex adjacent to the enhancing lesion is more frequently associated with HGG than CM.
引用
收藏
页码：713 / 717
页数：5
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