An overview on cardioprotective and anti-diabetic effects of thymoquinone

被引:47
作者
Farkhondeh, Tahereh [1 ,3 ]
Samarghandian, Saeed [2 ]
Borji, Abasalt [2 ]
机构
[1] Islamic Azad Univ, Mashhad Branch, Fac Med, Innovat Med Res Ctr, Mashhad, Iran
[2] Neyshabur Univ Med Sci, Dept Basic Med Sci, Neyshabur 1413993186, Iran
[3] Islamic Azad Univ, Dept Immunol, Innovat Med Res Ctr, Mashhad Branch, Mashhad, Iran
关键词
Thymoquinone; Antioxidant; Cardiovascular; Diabetes; Hyperlipidemia; SEED NIGELLA-SATIVA; DOXORUBICIN-INDUCED CARDIOTOXICITY; OXIDATIVE STRESS; POSSIBLE MECHANISM; VOLATILE OIL; ATHEROSCLEROSIS; ELUCIDATION; REDUCTION; COMPONENT; GLUCOSE;
D O I
10.1016/j.apjtm.2017.08.020
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Thymoquinone (TQ), one of the active components of Nigella sativa exhibited to have many biological effects. Several beneficial effects of TQ such as its antidiabetic, antioxidant, anticancer, hypolipidemic, and anti-inflammatory activities have been recognized. The present review focuses on the findings of recent studies on the protective effects of TQ against cardiovascular diseases. In the current review, we additionally concluded that TQ may be therapeutically effective agents for controlling diabetes and hyperlipidemia by decreasing the oxidative stress and inflammatory responses.
引用
收藏
页码:849 / 854
页数:6
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