The Search for Effective Treatment of Clostridium difficile Infection

被引：49
作者：
DuPont, Herbert L. [1 ,2 ]
机构：
[1] Univ Texas Houston, Sch Publ Hlth, St Lukes Episcopal Hosp, Baylor Coll Med, Houston, TX 77030 USA
[2] Kelsey Res Fdn, Houston, TX USA
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2011年 / 364卷 / 05期
关键词：
FIDAXOMICIN; OUTCOMES;
D O I：
10.1056/NEJMe1013236
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：473 / 475
页数：3
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共 10 条
[1]   Effects of Inoculum, pH, and Cations on the In Vitro Activity of Fidaxomicin (OPT-80, PAR-101) against Clostridium difficile [J].
Babakhani, F. ;
Seddon, J. ;
Robert, N. ;
Shue, Y. -K. ;
Sears, P. .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2010, 54 (06) :2674-2676
[2]   Clinical outcomes of intravenous immune globulin in severe Clostridium difficile-associated diarrhea [J].
Juang, Paul ;
Skledar, Susan J. ;
Zgheib, Nathalie K. ;
Paterson, David L. ;
Vergis, Emanuel N. ;
Shannon, William D. ;
Ansani, Nicole T. ;
Branch, Robert A. .
AMERICAN JOURNAL OF INFECTION CONTROL, 2007, 35 (02) :131-137
[3]   Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea [J].
Kyne, L ;
Warny, M ;
Qamar, A ;
Kelly, CP .
LANCET, 2001, 357 (9251) :189-193
[4]   The potential value of Clostridium difficile vaccine: An economic computer simulation model [J].
Lee, Bruce Y. ;
Popovich, Michael J. ;
Ye Tian ;
Bailey, Rachel R. ;
Ufberg, Paul J. ;
Wiringa, Ann E. ;
Muder, Robert R. .
VACCINE, 2010, 28 (32) :5245-5253
[5]   Fidaxomicin versus Vancomycin for Clostridium difficile Infection [J].
Louie, Thomas J. ;
Miller, Mark A. ;
Mullane, Kathleen M. ;
Weiss, Karl ;
Lentnek, Arnold ;
Golan, Yoav ;
Gorbach, Sherwood ;
Sears, Pamela ;
Shue, Youe-Kong .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (05) :422-431
[6]   Treatment with Monoclonal Antibodies against Clostridium difficile Toxins [J].
Lowy, Israel ;
Molrine, Deborah C. ;
Leav, Brett A. ;
Blair, Barbra M. ;
Baxter, Roger ;
Gerding, Dale N. ;
Nichol, Geoffrey ;
Thomas, William D., Jr. ;
Leney, Mark ;
Sloan, Susan ;
Hay, Catherine A. ;
Ambrosino, Donna M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 362 (03) :197-205
[7]   Breaking the cycle:: Treatment strategies for 163 cases of recurrent Clostridium difficile disease [J].
McFarland, LV ;
Elmer, GW ;
Surawicz, CM .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2002, 97 (07) :1769-1775
[8]   Management and outcomes of a first recurrence of Clostridium difficile-associated disease in Quebec, Canada [J].
Pépin, J ;
Routhier, S ;
Gagnon, S ;
Brazeau, I .
CLINICAL INFECTIOUS DISEASES, 2006, 42 (06) :758-764
[9]   Probiotics for treatment of Clostridium difficile-associated colitis in adults [J].
Pillai, A. ;
Nelson, R. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2008, (01)
[10]   A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficile-infected patients than does vancomycin [J].
Tannock, Gerald W. ;
Munro, Karen ;
Taylor, Corinda ;
Lawley, Blair ;
Young, Wayne ;
Byrne, Brendan ;
Emery, Judy ;
Louie, Thomas .
MICROBIOLOGY-SGM, 2010, 156 :3354-3359
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