A Simple and Effective Method for α-Hydroxylation of β-Dicarbonyl Compounds Using Oxone as an Oxidant without a Catalyst

被引：46

作者：

Yu, Jun ^{[1
]}

Cui, Jian ^{[1
]}

Zhang, Chi ^{[1
]}

机构：

[1] Nankai Univ, State Key Lab Elementoorgan Chem, Res Inst Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 2010卷 / 36期

基金：

中国国家自然科学基金;

关键词：

Synthetic methods; Oxidation; Hydroxylation; Enols; DYE-SENSITIZED PHOTOOXIDATION; 1,3-DICARBONYL COMPOUNDS; OXIDATIVE CLEAVAGE; KETO-ESTERS; ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC HYDROXYLATION; BIOMIMETIC SYNTHESIS; SELECTIVE CLEAVAGE; FACILE OXIDATION; SECONDARY-AMINES;

D O I：

10.1002/ejoc.201000940

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxone has been found to be a highly efficient reagent for the introduction of a hydroxy group at the a position of a variety of beta-dicarbonyl compounds in the homogeneous solvent mixture of water and 1,4-dioxane at 60 degrees C.

引用

页码：7020 / 7026

页数：7

共 74 条

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