Emulsions and microemulsions with a fluorocarbon phase

被引：66
|
作者：
Krafft, MP
Chittofrati, A
Riess, JG
机构：
[1] CNRS, Inst Charles Sadron, F-67083 Strasbourg, France
[2] Solvay Solexis, I-20021 Milan, Italy
[3] Univ Calif San Diego, MRI Inst, San Diego, CA 92103 USA
来源：
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE | 2003年 / 8卷 / 03期
关键词：
perfluorocarbon; emulsion; microemulsion; reverse emulsion; oxygen delivery; targeted emulsion; diagnosis; drug delivery; polymerization;
D O I：
10.1016/S1359-0294(03)00045-1
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
A phase III clinical study of a perfluorooctyl bromide emulsion demonstrated reduction and avoidance of donor blood transfusion in surgery. Novel fluorocarbon-in-water emulsions are being investigated, including emulsions highly stabilized by fluorocarbon-hydrocarbon diblocks and targeted emulsions for molecular imaging, diagnosis and drug delivery. Reverse water-influorocarbon emulsions and microemulsions that have potential for pulmonary drug delivery are also being studied. Microemulsions with highly fluorinated components are being actively investigated, with applications in polymerization technology and as research tools. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：251 / 258
页数：8
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