The infant microbiome development: mom matters

被引：649
作者：
Mueller, Noel T. [1 ,2 ,3 ]
Bakacs, Elizabeth [4 ]
Combellick, Joan [5 ]
Grigoryan, Zoya [4 ]
Dominguez-Bello, Maria G. [4 ]
机构：
[1] Columbia Univ, Med Ctr, Dept Epidemiol, Mailman Sch Publ Hlth, New York, NY USA
[2] Columbia Univ, Med Ctr, Coll Physicians & Surg, Inst Human Nutr, New York, NY USA
[3] Columbia Univ, Med Ctr, Dept Med, New York, NY USA
[4] NYU, Sch Med, Div Translat Med, New York, NY 10012 USA
[5] NYU, Sch Nursing, New York, NY USA
来源：
TRENDS IN MOLECULAR MEDICINE | 2015年 / 21卷 / 02期
关键词：
GUT MICROBIOTA; HUMAN-MILK; INTESTINAL MICROBIOTA; BREAST-MILK; NECROTIZING ENTEROCOLITIS; CESAREAN-SECTION; AMNIOTIC-FLUID; PREGNANT-WOMEN; DELIVERY MODE; DOUBLE-BLIND;
D O I：
10.1016/j.molmed.2014.12.002
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The infant microbiome plays an essential role in human health and its assembly is determined by maternal offspring exchanges of microbiota. This process is affected by several practices, including Cesarean section (C-section), perinatal antibiotics, and formula feeding, that have been linked to increased risks of metabolic and immune diseases. Here we review recent knowledge about the impacts on infant microbiome assembly, discuss preventive and restorative strategies to ameliorate the effects of these impacts, and highlight where research is needed to advance this field and improve the health of future generations.
引用
收藏
页码：109 / 117
页数：9
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