Natural variation at Strubbelig Receptor Kinase 3 drives immune-triggered incompatibilities between Arabidopsis thaliana accessions

被引：103
作者：
Alcazar, Ruben [1 ]
Garcia, Ana V. [2 ]
Kronholm, Ilkka [1 ]
de Meaux, Juliette [1 ]
Koornneef, Maarten [1 ]
Parker, Jane E. [2 ]
Reymond, Matthieu [1 ]
机构：
[1] Max Planck Inst Plant Breeding Res, Dept Plant Breeding & Genet, Cologne, Germany
[2] Max Planck Inst Plant Breeding Res, Dept Plant Microbe Interact, Cologne, Germany
来源：
NATURE GENETICS | 2010年 / 42卷 / 12期
关键词：
MPK4; ACTIVATION; RESISTANCE; EDS1; MEKK1;
D O I：
10.1038/ng.704
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Accumulation of genetic incompatibilities within species can lead to reproductive isolation and, potentially, speciation. In this study, we show that allelic variation at SRF3 (Strubbelig Receptor Family 3), encoding a receptor-like kinase, conditions the occurrence of incompatibility between Arabidopsis thaliana accessions. The geographical distribution of SRF3 alleles reveals that allelic forms causing epistatic incompatibility with a Landsberg erecta allele at the RPP1 resistance locus are present in A. thaliana accessions in central Asia. Incompatible SRF3 alleles condition for an enhanced early immune response to pathogens as compared to the resistance-dampening effect of compatible SRF3 forms in isogenic backgrounds. Variation in disease susceptibility suggests a basis for the molecular patterns of a recent selective sweep detected at the SRF3 locus in central Asian populations.
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收藏
页码：1135 / +
页数：6
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