Kaffir lime leaf extract mediated synthesis, anticancer activities and antibacterial kinetics of Ag and Ag/AgCl nanoparticles

被引：18

作者：

Chankaew, Chaiyos ^{[1
,2
]}

Somsri, Supattra ^{[1
,3
]}

Tapala, Weerinradah ^{[4
]}

Mahatheeranont, Sugunya ^{[1
]}

Saenjum, Chalermpong ^{[5
]}

Rujiwatra, Apinpus ^{[1
]}

机构：

[1] Chiang Mai Univ, Dept Chem, Fac Sci, Chiang Mai 50200, Thailand

[2] Chiang Mai Univ, Grad Sch, Chiang Mai 50200, Thailand

[3] Chiang Mai Univ, Environm Sci Res Ctr, Fac Sci, Chiang Mai 50200, Thailand

[4] Maejo Univ, Dept Chem, Fac Sci, Chiang Mai 50290, Thailand

[5] Chiang Mai Univ, Dept Pharmaceut Sci, Fac Pharm, Chiang Mai 50200, Thailand

来源：

PARTICUOLOGY | 2018年 / 40卷

关键词：

Phytosynthesis; Silver; Silver chloride; Nanoparticle; Antimicrobial; Anticancer; SILVER NANOPARTICLES; GREEN SYNTHESIS; ANTIMICROBIAL ACTIVITY; CYTOTOXICITY; NANOSILVER; COMPOUND; STRESS; CELLS; MODEL; SIZE;

D O I：

10.1016/j.partic.2017.11.003

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

A facile phytosynthesis of Ag/AgCl and Ag nanoparticles (NPs) was developed using a crude water extract of Citrus hystrix DC (kaffir lime) leaves. The phytochemical and chloride contents of the extract, and various synthesis parameters were studied. The obtained Ag/AgCI and Ag NPs were of the cubic phase and mostly spherical in shape. Particle sizes of the yielded NPs were distributed in a narrow range with an average size of 20 and 38 nm for the Ag/AgCI and Ag NPs, respectively. The reducing function of the phytochemicals and the stabilizing ability of gelatin were demonstrated. The NPs showed significant anti proliferative activities against the carcinoma HCT 116 and adenocarcinoma Caco-2 colorectal cell lines, but had a negative effect toward human fibroblasts. The NPs exhibited excellent antibacterial activities against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus cereus. The inactivation kinetics obtained in the presence of the NPs showed a biphasic behavior that can be explained by the Cerf model. (C) 2018 Chinese Society of Particuology and Institute of Process Engineering, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.

引用

页码：160 / 168

页数：9

共 43 条

[1] A modified Weibull model for bacterial inactivation [J].