1-Phenylisoquinoline larvicidal activity against Culex quinquefasciatus

被引：7

作者：

Quevedo, Rodolfo ^{[1
]}

Baquero, Edwin ^{[1
]}

Quinones, Martha L. ^{[2
]}

机构：

[1] Univ Nacl Colombia, Fac Ciencias, Dept Quim, Bogota, Colombia

[2] Univ Nacl Colombia, Fac Med, Dept Salud Publ, Bogota, Colombia

来源：

NATURAL PRODUCT RESEARCH | 2012年 / 26卷 / 12期

关键词：

Pictet-Spengler; isoquinoline; alkaloid; Culex quinquefasciatus; dopamine; Berberis; ALKALOIDS; PATTERN;

D O I：

10.1080/14786419.2011.560846

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The larvicidal potential of several dopamine 1-phenylisoquinoline derivatives against Culex quinquefasciatus third instar larvae was investigated in a rational search for insecticides. The results showed that these isoquinolines presented moderate larvicidal activity, that the presence of a substituent is needed on carbon 1 for such activity to be presented and that it may be possible to develop novel insecticidal compounds having potential use in controlling insects by appropriate structural modification of 1-phenylisoquinolines. This article presents a possible structure-larvicidal activity relationship for isoquinolinic compounds.

引用

页码：1094 / 1100

页数：7

共 16 条

[1]

Álvarez Leslie, 2006, Rev. Colomb. Entomol., V32, P172

[2] Non-antibiotic anti-diarrhoeal drugs: Factors affecting oral bioavailability of berberine and loperamide in intestinal tissue [J].

Baird, AW ;

Taylor, CT ;

Brayden, DJ .

ADVANCED DRUG DELIVERY REVIEWS, 1997, 23 (1-3) :111-120

[3]

Bisset J, 1998, Rev Cubana Med Trop, V50, P133

[4] THE PICTET-SPENGLER CONDENSATION - A NEW DIRECTION FOR AN OLD REACTION [J].

COX, ED ;

COOK, JM .

CHEMICAL REVIEWS, 1995, 95 (06) :1797-1842

[5]

FAJARDO V, 1986, REV LATINOAM QUIM, V16, P141

[6]

FINNEY DJ, 1948, BIOMETRIKA, V35, P191, DOI 10.2307/2332639

[7] Botanical insecticides, deterrents, and repellents in modern agriculture and an increasingly regulated world [J].

Isman, MB .

ANNUAL REVIEW OF ENTOMOLOGY, 2006, 51 :45-66

[8] SOME DIMERIC BENZYLISOQUINOLINE ALKALOIDS WITH AN UNUSUAL OXYGENATION PATTERN [J].

LEET, JE ;

FAJARDO, V ;

FREYER, AJ ;

SHAMMA, M .

JOURNAL OF NATURAL PRODUCTS, 1983, 46 (06) :908-912

[9] Exploration of larvicidal and adult emergence inhibition activities of Ricinus communis seed extract against three potential mosquito vectors in Kolkata, India [J].

Mandal, Shyamapada .

ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2010, 3 (08) :605-609

[10]

McLaughlin JL, 1998, DRUG INF J, V32, P513, DOI 10.1177/009286159803200223

← 1 2 →