Manganese oxide nanoparticles supported on graphene oxide as an efficient nanocatalyst for the synthesis of 1,2,4-oxadiazoles from aldehydes

The easy synthesis of graphene oxide (GO)-supported manganese dioxide (MnO2) nanoparticles as a stable heterogeneous nanocatalyst (MnO2@GO) is described. This catalyst was investigated in the synthesis of 1,2,4-oxadiazoles from amidoximes and aldehydes via a cyclization and oxidation process. The nanocomposite was prepared and characterized using various techniques. The catalytic application of the nanocomposite was examined in the reaction of a variety of aldehydes with aliphatic and aromatic amidoximes. The stable and robust catalyst was recycled for seven consecutive runs without a significant decrease in the catalytic activity.