Advanced Nano-Carriers for Anti-Tumor Drug Loading

被引:23
|
作者
Xiang, Jia [1 ]
Zhao, Rui [1 ]
Wang, Bo [1 ]
Sun, Xinran [1 ]
Guo, Xu [1 ]
Tan, Songwen [1 ]
Liu, Wenjie [1 ]
机构
[1] Cent South Univ, Xiangya Sch Pharmaceut Sci, Changsha, Peoples R China
来源
FRONTIERS IN ONCOLOGY | 2021年 / 11卷
关键词
cancer; chemotherapy; antitumor drug; nano drug carrier; targeted transportation; NANOSTRUCTURED LIPID CARRIERS; IN-VITRO; INORGANIC NANOPARTICLES; MAGNETIC NANOPARTICLES; TRIGGERED RELEASE; TARGETED DELIVERY; PLA NANOPARTICLES; NONVIRAL VECTORS; CANCER-THERAPY; GENE DELIVERY;
D O I
10.3389/fonc.2021.758143
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Chemotherapy is one of the important means of tumor therapy. However, most of the anti-tumor drugs that currently used in clinic are hydrophobic non-specific drugs, which seriously affect the efficacy of drugs. With the development of nanotechnology, drug efficacy can be improved by selecting appropriate biodegradable nanocarriers for achieving the controlled release, targeting and higher bioavailability of drugs. This paper reviewed the research progress of anti-tumor drug nanoparticle carriers, which mainly summarized the materials used for anti-tumor drug nanoparticle carriers and their effects in anti-tumor drugs, as well as the targeted drug delivery methods of anti-tumor drugs based on nanocarriers.
引用
收藏
页数:7
相关论文
共 50 条
  • [41] Biophysical Characterization of Glycodendrimers As Nano-carriers for HIV Peptides
    Ionov, M.
    Ciepluch, K.
    Moreno, B. R.
    Appelhans, D.
    Sanchez-Nieves, J.
    Gomez, R.
    de la Mata, F. J.
    Munoz-Fernandez, M. A.
    Bryszewska, M.
    CURRENT MEDICINAL CHEMISTRY, 2013, 20 (31) : 3935 - 3943
  • [42] THE DEVELOPMENT OF SPARSOMYCIN AS AN ANTI-TUMOR DRUG
    OTTENHEIJM, HCJ
    VANDENBROEK, LAGM
    ANTI-CANCER DRUG DESIGN, 1988, 2 (04): : 333 - 337
  • [43] ANTI-TUMOR ANTIBODIES AS CARRIERS OF RADIONUCLEIDES AND CYTOTOXIC DRUGS
    GHOSE, T
    TAI, J
    BLAIR, AH
    BELITSKY, P
    AQUINO, J
    NORVELL, ST
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1978, 19 (MAR): : 236 - 236
  • [44] ANTI-TUMOR ANTIBODIES AS CARRIERS OF RADIONUCLIDES AND CYTOTOXIC AGENTS
    GHOSE, T
    TAI, J
    BLAIR, AH
    FEDERATION PROCEEDINGS, 1978, 37 (06) : 1761 - 1761
  • [45] Stabilization of Aerosolizable Nano-carriers by Freeze-Drying
    Packhaeuser, Claudia B.
    Lahnstein, Kerstin
    Sitterberg, Johannes
    Schmehl, Thomas
    Gessler, Tobias
    Bakowsky, Udo
    Seeger, Werner
    Kissel, Thomas
    PHARMACEUTICAL RESEARCH, 2009, 26 (01) : 129 - 138
  • [46] Drug -driven self-assembly of pH-sensitive nano-vesicles with high loading capacity and anti-tumor efficacy†
    Zhai, Yaomin
    Wang, Juan
    Qiu, Liyan
    BIOMATERIALS SCIENCE, 2021, 9 (09) : 3348 - 3361
  • [47] Bacteria and cells as alternative nano-carriers for biomedical applications
    Garcia-Alvarez, Rafaela
    Vallet-Regi, Maria
    EXPERT OPINION ON DRUG DELIVERY, 2022, 19 (01) : 103 - 118
  • [48] Nano-carriers for targeted delivery and biomedical imaging enhancement
    Parekh, Gaurav
    Shi, Yuanyuan
    Zheng, Juanjuan
    Zhang, Xingcai
    Leporatti, Stefano
    THERAPEUTIC DELIVERY, 2018, 9 (06) : 451 - 468
  • [49] Hyperbranched dendritic nano-carriers for topical delivery of dithranol
    Agrawal, Udita
    Mehra, Neelesh Kumar
    Gupta, Umesh
    Jain, N. K.
    JOURNAL OF DRUG TARGETING, 2013, 21 (05) : 497 - 506
  • [50] Stabilization of Aerosolizable Nano-carriers by Freeze-Drying
    Claudia B. Packhaeuser
    Kerstin Lahnstein
    Johannes Sitterberg
    Thomas Schmehl
    Tobias Gessler
    Udo Bakowsky
    Werner Seeger
    Thomas Kissel
    Pharmaceutical Research, 2009, 26 : 129 - 138