Advanced Nano-Carriers for Anti-Tumor Drug Loading

被引:23
|
作者
Xiang, Jia [1 ]
Zhao, Rui [1 ]
Wang, Bo [1 ]
Sun, Xinran [1 ]
Guo, Xu [1 ]
Tan, Songwen [1 ]
Liu, Wenjie [1 ]
机构
[1] Cent South Univ, Xiangya Sch Pharmaceut Sci, Changsha, Peoples R China
来源
FRONTIERS IN ONCOLOGY | 2021年 / 11卷
关键词
cancer; chemotherapy; antitumor drug; nano drug carrier; targeted transportation; NANOSTRUCTURED LIPID CARRIERS; IN-VITRO; INORGANIC NANOPARTICLES; MAGNETIC NANOPARTICLES; TRIGGERED RELEASE; TARGETED DELIVERY; PLA NANOPARTICLES; NONVIRAL VECTORS; CANCER-THERAPY; GENE DELIVERY;
D O I
10.3389/fonc.2021.758143
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Chemotherapy is one of the important means of tumor therapy. However, most of the anti-tumor drugs that currently used in clinic are hydrophobic non-specific drugs, which seriously affect the efficacy of drugs. With the development of nanotechnology, drug efficacy can be improved by selecting appropriate biodegradable nanocarriers for achieving the controlled release, targeting and higher bioavailability of drugs. This paper reviewed the research progress of anti-tumor drug nanoparticle carriers, which mainly summarized the materials used for anti-tumor drug nanoparticle carriers and their effects in anti-tumor drugs, as well as the targeted drug delivery methods of anti-tumor drugs based on nanocarriers.
引用
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页数:7
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