Fertility Issues in Pediatric Urology

被引:3
作者
Kieran, Kathleen [1 ]
Shnorhavorian, Margarett [1 ]
机构
[1] Seattle Childrens Hosp, Div Urol, 4800 Sand Point Way Northeast,OA-9-220, Seattle, WA 98105 USA
关键词
Fertility; Oncology; Differences in sexual differentiation; Pediatric; OVARIAN TISSUE CRYOPRESERVATION; CONGENITAL ADRENAL-HYPERPLASIA; REPRODUCTIVE HORMONE-LEVELS; ANTI-MULLERIAN HORMONE; YOUNG-ADULT PATIENTS; LEYDIG-CELL FUNCTION; CHILDHOOD-CANCER; SPERM CRYOPRESERVATION; RHEUMATOID-ARTHRITIS; KLINEFELTER SYNDROME;
D O I
10.1016/j.ucl.2018.06.006
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Improved understanding of the pathogenesis and natural history of many urologic disorders, as well as advances in fertility preservation techniques, has increased the awareness of and options for management of fertility threats in pediatric patients. In children, fertility may be altered by oncologic conditions, by differences in sexual differentiation, by gonadotoxic drugs and other side effects of treatment for nonurologic disorders, and by urologic conditions, such as varicocele and cryptorchidism. Although fertility concerns are best addressed in a multidisciplinary setting, pediatric urologists should be aware of the underlying pathophysiology and management options to properly counsel and advocate for patients.
引用
收藏
页码:587 / +
页数:14
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