Review on Research about Traditional Chinese Medicine in Cancer Stem Cell

被引:9
|
作者
Wang, Yaohan [1 ]
Feng, Li [2 ,3 ]
Piao, Bingkui [1 ]
Zhang, Peitong [1 ]
机构
[1] China Acad Chinese Med Sci, Guanganmen Hosp, Dept Oncol, 5 Beixiange, Beijing 100053, Peoples R China
[2] Chinese Acad Med Sci, Canc Hosp, Natl Canc Ctr, Tradit Chinese Med Dept, Beijing 100021, Peoples R China
[3] Peking Union Med Coll, Beijing 100021, Peoples R China
基金
中国国家自然科学基金;
关键词
BUFALIN-INDUCED APOPTOSIS; ACUTE MYELOID-LEUKEMIA; TZE HUANG SUPPRESSES; COLORECTAL-CANCER; PROLIFERATION; AUTOPHAGY; ACTIVATION; MECHANISMS; STAT3; MODEL;
D O I
10.1155/2017/4505194
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Cancer stem cells (CSCs) are small subpopulations of neoplastic cells within a tumor, which have self-renewal and differentiation abilities and could generate new tumors with few cells. Researches have showed that CSCs are considered the most likely reason for cancer recurrence and metastasis. Accumulating evidences have showed that traditional Chinese medicine (TCM) has significant effect on CSCs. It could inhibit the proliferation, self-renew, and multidifferentiation of CSCs. We aimed to summarize the theories of CSCs in TCM, the inhibitory effect, and the pathway on CSCs of TCM. This review will provide potential new strategies and alternative perspectives for CSCs treatments and basic research into complementary and alternative medicine.
引用
收藏
页数:10
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