Synthesis of C40-Symmetrical Fully Conjugated Carotenoids by Olefin Metathesis

被引：19

作者：

Fontan, Noelia ^{[1
]}

Dominguez, Marta ^{[1
]}

Alvarez, Rosana ^{[1
]}

de Lera, Angel R. ^{[1
]}

机构：

[1] Univ Vigo, Dept Quim Organ, Fac Quim, Vigo 36310, Spain

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 2011卷 / 33期

关键词：

Polyenes; Polyolefins; Terpenoids; Carotenoids; Metathesis; STILLE REACTION; IN-SITU; EFFICIENT; RUTHENIUM; CATALYSTS; HYDROZIRCONATION; PYRRHOXANTHIN; REARRANGEMENT; BUTENOLIDE; COMPLEXES;

D O I：

10.1002/ejoc.201100935

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In an effort to push olefin metathesis to the limits of conjugation in reactants and products, the C-40-symmetrical carotenoids beta,beta-carotene (1), lycopene (2), (3R,3'R)-zeaxanthin (3), and rac-isozeaxanthin (4), which are conjugated undecaenes, have been synthesized from C-21-terminal hexaenes by treatment with Grubbs' second-generation Ru catalyst in dichloromethane at 50 degrees C.

引用

页码：6704 / 6712

页数：9

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