Bilayer hydrogel assembly

被引：12

作者：

Kuckling, Dirk ^{[1
]}

Pareek, Pradeep ^{[1
]}

机构：

[1] Tech Univ Dresden, Fachrichtung Chem & Lebensmittelchem, D-01062 Dresden, Germany

来源：

POLYMER | 2008年 / 49卷 / 06期

关键词：

hydrogel; lithography; stimuli-sensitive polymers;

D O I：

10.1016/j.polymer.2008.01.069

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The combination of two hydrogel layers based on photo-cross-linkable poly(dimethyl acrylamide) (PDMAAm) as base layer and poly(N-isopropyl acrylamide) (PNIPAAm) as top layer forms a bilayer assembly where, the base layer is highly swollen and the top layer shows temperature responsive swelling. Characterization was done by a combination of surface plasmon resonance spectroscopy and optical waveguide spectroscopy as well as atomic force microscopy. The PDMAAm and PNIPAAm within the bilayer assembly retain their swelling behavior, which they showed as a separate layer. Due to the presence of the photo-cross-linker such bilayer films can be patterned to develop surfaces with different properties at different regions. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1435 / 1439

页数：5

共 18 条

[1] Release characteristics of novel pH-sensitive p(HEMA-DMAEMA) hydrogels containing 3-(trimethoxy-silyl) propyl methacrylate [J].

Brahim, S ;

Narinesingh, D ;

Guiseppi-Elie, A .

BIOMACROMOLECULES, 2003, 4 (05) :1224-1231

[2] Mixed polymer brushes by sequential polymer addition: Anchoring layer effect [J].

Draper, J ;

Luzinov, I ;

Minko, S ;

Tokarev, I ;

Stamm, M .

LANGMUIR, 2004, 20 (10) :4064-4075

[3] Copolymerization of 2-carboxyisopropylacrylamide with N-isopropylacrylamide accelerates cell detachment from grafted surfaces by reducing temperature [J].

Ebara, M ;

Yamato, M ;

Hirose, M ;

Aoyagi, T ;

Kikuchi, A ;

Sakai, K ;

Okano, T .

BIOMACROMOLECULES, 2003, 4 (02) :344-349

[4] Polymers as dewetting agents [J].

Fondecave, R ;

Wyart, FB .

MACROMOLECULES, 1998, 31 (26) :9305-9315

[5] Molecular weight and polydispersity estimation of adsorbing polymer brushes by atomic force microscopy [J].

Goodman, D ;

Kizhakkedathu, JN ;

Brooks, DE .

LANGMUIR, 2004, 20 (08) :3297-3303

[6] Photo-cross-linkable PNIPAAm copolymers. 4. Effects of copolymerization and cross-linking on the volume-phase transition in constrained hydrogel layers [J].

Harmon, ME ;

Kuckling, D ;

Pareek, P ;

Frank, CW .

LANGMUIR, 2003, 19 (26) :10947-10956

[7] Hydrogels for biomedical applications [J].

Hoffman, Allan S. .

ADVANCED DRUG DELIVERY REVIEWS, 2012, 64 :18-23

[8]

Hoffman AS, 2000, CLIN CHEM, V46, P1478

[9] Photopatterning of thermally sensitive hydrogels useful for microactuators [J].

Hoffmann, J ;

Plötner, M ;

Kuckling, D ;

Fischer, WJ .

SENSORS AND ACTUATORS A-PHYSICAL, 1999, 77 (02) :139-144

[10] Recent developments in the properties and applications of polyelectrolyte multilayers [J].

Jaber, Jad A. ;

Schlenoff, Joseph B. .

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE, 2006, 11 (06) :324-329

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