Pre-Exposure Prophylaxis (PrEP) Adherence Questionnaire: Psychometric Validation among Sexually Transmitted Infection Patients in China

被引：5

作者：

Yu, Xiaoyue ^{[1
]}

Xu, Chen ^{[1
]}

Ni, Yang ^{[1
,2
]}

Chang, Ruijie ^{[1
]}

Wang, Huwen ^{[1
]}

Gong, Ruijie ^{[1
,3
]}

Wang, Ying ^{[1
]}

Wang, Suping ^{[1
]}

Cai, Yong ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Publ Hlth, Sch Med, Shanghai 200003, Peoples R China

[2] Shanghai Skin Dis Hosp, Shanghai 200040, Peoples R China

[3] Shanghai Xuhui Ctr Dis Control & Prevent, Shanghai 200030, Peoples R China

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | 2021年 / 18卷 / 20期

关键词：

pre-exposure prophylaxis (PrEP); HIV prevention; questionnaire; adherence; TRANSGENDER WOMEN; HIV-INFECTION; MEN; SEX; ACCEPTABILITY; FACILITATORS; BARRIERS; RISK; DISABILITY; PREVENTION;

D O I：

10.3390/ijerph182010980

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Background: Ensuring adherence guarantees the efficacy of pre-exposure prophylaxis (PrEP). Methods: We conducted a cross-sectional study among 816 sexually transmitted infection (STI) patients in Shanghai. The questionnaire included self-reported demographic characteristics, self-administered items on adherence to free oral PrEP, and PrEP uptake behavior measurement. We conducted item analysis, reliability analysis, validity analysis and receiver operating characteristic (ROC) curve analysis. Results: Not all items were considered acceptable in the item analysis. The questionnaire had a McDonald's omega coefficient of 0.847. The scale-level content validity index (CVI) was 0.938 and the item-level CVI of each item ranged from 0.750 to 1. In exploratory factor analysis, we introduced a four-factor model accounting for 79.838% of the aggregate variance, which was validated in confirmatory factor analysis. Adding PrEP adherence questionnaire scores contributed to prediction of PrEP uptake behavior (p < 0.001) in regression analysis. The maximum area under the ROC curve was 0.778 (95% IC: 0.739-0.817). Conclusion: The PrEP adherence questionnaire presented psychometric validation among STI patients.

引用

页数：12

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