[3+2] Cycloaddition of Methylenedihydrobenzofurandiones and Nitrilimines: Synthesis of Sipropyrazole Compounds

被引：2

作者：

Shi, Wangyu ^{[1
]}

Xu, Jiaqing ^{[1
]}

Mao, Biming ^{[1
]}

Jia, Hao ^{[1
]}

Huang, Jiaxing ^{[1
]}

Guo, Hongchao ^{[1
]}

机构：

[1] China Agr Univ, Coll Sci, Dept Chem, Beijing 100193, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 40卷 / 03期

基金：

中国国家自然科学基金;

关键词：

cycloaddition; nitrilimine; spirocyclic compound; pyrazole; BAYLIS-HILLMAN CARBONATES; ENANTIOSELECTIVE 1,3-DIPOLAR CYCLOADDITIONS; C; N-CYCLIC AZOMETHINE IMINES; NITRILE IMINES; 1.3-DIPOLARE ADDITIONEN; INSECTICIDAL ACTIVITIES; BIOLOGICAL EVALUATION; FACILE SYNTHESIS; PYRAZOLE AMIDES; 4+3 ANNULATION;

D O I：

10.6023/cjoc201907030

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The [3+2] cycloaddition of methylenedihydrobenzofurandiones and nitrilimines worked efficiently in CHCl3 at room temperature in the presence of Et3N, producing biologically interesting spirocyclic pyrazole derivatives in high yield (78%similar to 94%) with excellent diastereoselectivity.

引用

页码：756 / 762

页数：7

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